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ETV4 anticorps (AA 50-109)

ETV4 Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 1A2G3 unconjugated
N° du produit ABIN969121
  • Antigène Voir toutes ETV4 Anticorps
    ETV4 (Ets Variant 4 (ETV4))
    Épitope
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 50-109
    Reactivité
    • 27
    • 22
    • 14
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 25
    • 1
    • 1
    Souris
    Clonalité
    • 26
    • 1
    Monoclonal
    Conjugué
    • 20
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ETV4 est non-conjugé
    Application
    • 17
    • 10
    • 8
    • 6
    • 5
    • 4
    • 1
    Western Blotting (WB), ELISA
    Purification
    purified
    Immunogène
    Purified recombinant fragment of human ETV4 (aa50-109) expressed in E. coli.
    Clone
    1A2G3
    Isotype
    IgG1
    Top Product
    Discover our top product ETV4 Anticorps primaire
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Yu, Xia, Wang, Wang, Pan, Kwong, Hortobagyi, Hung: "Antitumor activity of an Ets protein, PEA3, in breast cancer cell lines MDA-MB-361DYT2 and BT474M1." dans: Molecular carcinogenesis, Vol. 45, Issue 9, pp. 667-75, (2006) (PubMed).

    Matsui, Sugimori, Motomura, Ejiri, Tsukada, Kitajima: "PEA3 cooperates with c-Jun in regulation of HER2/neu transcription." dans: Oncology reports, Vol. 16, Issue 1, pp. 153-8, (2006) (PubMed).

    Zhu, Jiang, Shen, Wang, Zong, Li, Yang, Niu, Liu, Chen, Hu, Gu: "Elevated beta1,4-galactosyltransferase I in highly metastatic human lung cancer cells. Identification of E1AF as important transcription activator." dans: The Journal of biological chemistry, Vol. 280, Issue 13, pp. 12503-16, (2005) (PubMed).

  • Antigène
    ETV4 (Ets Variant 4 (ETV4))
    Autre désignation
    ETV4 (ETV4 Produits)
    Synonymes
    anticorps E1A-F, anticorps E1AF, anticorps PEA3, anticorps PEAS3, anticorps Pea3, anticorps AW414408, anticorps Pea-3, anticorps pea3, anticorps ETS variant 4, anticorps ets variant 4, anticorps ETV4, anticorps Etv4, anticorps etv4
    Sujet

    Description: ETV4: ets variant gene 4 (E1A enhancer binding protein, E1AF), also known as PEA3. Several members of the Ets gene family are known to encode sequencespecific DNA binding proteins. These include mouse PU.1, mouse and human Ets-1, Drosophila E74, chicken and human Ets-2 and rat GABP-α. Each of these proteins recognizes similar motifs in DNA that share a centrally located 5'-GGAA-3' element. For instance, PEA3 binds the motif 5'-AGGAAG-3' (the PEA-3 motif), but does not bind to the sequence 5'-AGGAAC-3', recognized by PU.1, although PU.1 binds equally well to both sequences. It appears that all of the Ets proteins recognize the same central core sequence but that each protein interacts with unique sequences that flank this core. PEA3 is expressed at readily detectable levels in cells of epithelial and fibroblastic origin but is not expressed in hematopoietic cells. This is in contrast to other members of the Ets gene family, such as Ets-1, Ets-2 and Fli-1, each of which is expressed primarily in cells of hematopoietic origin.

    Aliases: HGK, NIK, PEA3

    Poids moléculaire
    54 kDa
    ID gène
    2118
    HGNC
    2118
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