FABP2 anticorps

N° du produit ABIN969124

Détail du produit anti-FABP2 anticorps

Antigène: FABP2 (Fatty Acid Binding Protein 2, Intestinal (FABP2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FABP2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Fonction: FABP2 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human FABP2 expressed in E. Coli.

Clone: 9A9B7B3

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-FABP2 (ABIN969124)

Fisher, Li, Burwinkel, Kühr, Hoffmann, Möhlig, Spranger, Pfeiffer, Boeing, Schrezenmeir, Döring: "Preliminary evidence of FABP2 A54T polymorphism associated with reduced risk of type 2 diabetes and obesity in women from a German cohort." dans: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme, Vol. 38, Issue 5, pp. 341-5, (2006) (PubMed).

Kim, Yun, Byun, Yoo, Lee, Suh: "Codon 54 polymorphism of the fatty acid binding protein 2 gene is associated with increased fat oxidation and hyperinsulinemia, but not with intestinal fatty acid absorption in Korean men." dans: Metabolism: clinical and experimental, Vol. 50, Issue 4, pp. 473-6, (2001) (PubMed).

Georgopoulos, Aras, Tsai: "Codon-54 polymorphism of the fatty acid-binding protein 2 gene is associated with elevation of fasting and postprandial triglyceride in type 2 diabetes." dans: The Journal of clinical endocrinology and metabolism, Vol. 85, Issue 9, pp. 3155-60, (2000) (PubMed).

Détails sur FABP2

Antigène: FABP2 (Fatty Acid Binding Protein 2, Intestinal (FABP2))

Autre désignation: FABP2 (FABP2 Produits)

Synonymes: anticorps I-FABP, anticorps ifabp, anticorps zgc:92264, anticorps IFABP, anticorps fabpi, anticorps i-fabp, anticorps fabp2-A, anticorps FABP2, anticorps FABPI, anticorps FABP, anticorps Fabpi, anticorps fabp2, anticorps fabp2a, anticorps fatty acid binding protein 2, intestinal, anticorps fatty acid binding protein 2, anticorps fatty acid binding protein 2 L homeolog, anticorps fabp2, anticorps FABP2, anticorps Fabp2, anticorps fabp2.L

Sujet:

Description:

The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance. Genetic variation in FABP2 may thus contribute to interindividual variation in the response of plasma lipoproteins to different dietary fibres, but the mechanism does not appear to be related to increases in fecal bile acid secretion.

Aliases: FABPI, I-FABP, MGC133132, FABP2

Poids moléculaire: 15kDa

ID gène: 2169

HGNC: 2169

UniProt: P12104