FGG anticorps

N° du produit ABIN969142

Détail du produit anti-FGG anticorps

Antigène: FGG (Fibrinogen gamma Chain (FGG))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FGG est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Fonction: FGG Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human FGG expressed in E. Coli.

Clone: 4H9

Isotype: IgG2a

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-FGG (ABIN969142)

Uitte de Willige, Standeven, Philippou, Ariëns: "The pleiotropic role of the fibrinogen gamma' chain in hemostasis." dans: Blood, Vol. 114, Issue 19, pp. 3994-4001, (2009) (PubMed).

Bowley, Okumura, Lord: "Impaired protofibril formation in fibrinogen gamma N308K is due to altered D:D and "A:a" interactions." dans: Biochemistry, Vol. 48, Issue 36, pp. 8656-63, (2009) (PubMed).

Détails sur FGG

Antigène: FGG (Fibrinogen gamma Chain (FGG))

Autre désignation: FGG (FGG Produits)

Synonymes: anticorps FXII, anticorps HAF, anticorps 3010002H13Rik, anticorps AI256424, anticorps fibrinogen, anticorps FGG, anticorps LOC100220680, anticorps fb60h05, anticorps fb62e01, anticorps wu:fb60h05, anticorps wu:fb62e01, anticorps zgc:56023, anticorps fibrinogen gamma chain, anticorps coagulation factor XII (Hageman factor), anticorps fibrinogen gamma chain L homeolog, anticorps FGG, anticorps F12, anticorps fgg, anticorps Fgg, anticorps fgg.L, anticorps CpipJ_CPIJ006387, anticorps CpipJ_CPIJ010087

Sujet:

Description: The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.

Aliases: FGG

Poids moléculaire: 52kDa

ID gène: 2266

HGNC: 2266

UniProt: P02679