FOXD3 anticorps
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- Antigène Voir toutes FOXD3 Anticorps
- FOXD3 (Forkhead Box D3 (FOXD3))
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Reactivité
- Humain, Souris, Singe
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp FOXD3 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Purification
- purified
- Immunogène
- Purified recombinant fragment of human FOXD3 expressed in E. coli.
- Clone
- 5G9
- Isotype
- IgG1
- Top Product
- Discover our top product FOXD3 Anticorps primaire
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- Indications d'application
- ELISA: 1:10000, WB: 1:500 - 1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- 4°C, -20°C for long term storage
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Analyses of the effects that disease-causing missense mutations have on the structure and function of the winged-helix protein FOXC1." dans: American journal of human genetics, Vol. 68, Issue 3, pp. 627-41, (2001) (PubMed).
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Analyses of the effects that disease-causing missense mutations have on the structure and function of the winged-helix protein FOXC1." dans: American journal of human genetics, Vol. 68, Issue 3, pp. 627-41, (2001) (PubMed).
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- Antigène
- FOXD3 (Forkhead Box D3 (FOXD3))
- Autre désignation
- FOXD3 (FOXD3 Produits)
- Synonymes
- anticorps AIS1, anticorps Genesis, anticorps HFH2, anticorps VAMAS2, anticorps CWH3, anticorps Hfh2, anticorps fkd6, anticorps fkh6, anticorps forkhead-6, anticorps zgc:111934, anticorps XFD-6, anticorps xfoxd3, anticorps FOXD3, anticorps genesis, anticorps hfh2, anticorps foxd3b, anticorps foxd3b-A, anticorps forkhead box D3, anticorps forkhead box D3 L homeolog, anticorps forkhead box D3 S homeolog, anticorps FOXD3, anticorps Foxd3, anticorps foxd3, anticorps foxd3.L, anticorps foxd3.S
- Sujet
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Description: FoxD3 is a member of the Forkhead Box family and is characterized by a winged-helix DNA-binding structure and the important role it plays in embryonic development . This transcriptional regulator is required for the maintenance of pluripotency in the pre-implantation and peri-implantation stages of mouse embryonic development and is also required for trophoblast formation . FoxD3 is required for the maintenance of the mammalian neural crest, FoxD3(-/-) mouse embryos fail around the time of implantation with loss of neural crest-derived structures . FoxD3 also forms a regulatory network with Oct-4 and NANOG to maintain the pluripotency of ES cells .Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis .Tissue specificity: Expressed in chronic myeloid leukemia, Jurkat T-cell leukemia and teratocarcinoma cell lines, but not in any other cell lines or normal tissues examined .
Aliases: AIS1, HFH2, Genesis, FOXD3
- Poids moléculaire
- 48 kDa
- ID gène
- 27022
- HGNC
- 27022
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