FOXP2 anticorps

N° du produit ABIN969154

Détail du produit anti-FOXP2 anticorps

Antigène: FOXP2 (Forkhead Box P2 (FOXP2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FOXP2 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: purified

Immunogène: Purified recombinant fragment of human MAPK3 expressed in E. coli.

Clone: 5C11A8

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Références pour anticorps anti-FOXP2 (ABIN969154)

Konopka, Bomar, Winden, Coppola, Jonsson, Gao, Peng, Preuss, Wohlschlegel, Geschwind: "Human-specific transcriptional regulation of CNS development genes by FOXP2." dans: Nature, Vol. 462, Issue 7270, pp. 213-7, (2009) (PubMed).

Ptak, Enard, Wiebe, Hellmann, Krause, Lachmann, Pääbo: "Linkage disequilibrium extends across putative selected sites in FOXP2." dans: Molecular biology and evolution, Vol. 26, Issue 10, pp. 2181-4, (2009) (PubMed).

Détails sur FOXP2

Antigène: FOXP2 (Forkhead Box P2 (FOXP2))

Autre désignation: FOXP2 (FOXP2 Produits)

Synonymes: anticorps CAGH44, anticorps SPCH1, anticorps TNRC10, anticorps 2810043D05Rik, anticorps AI449000, anticorps CAG-16, anticorps D0Kist7, anticorps RGD1559697, anticorps FOXP2, anticorps spch1, anticorps cagh44, anticorps tnrc10, anticorps xlFoxP2, anticorps foxP2, anticorps foxP, anticorps Foxp2, anticorps foxP2b, anticorps foxp2a, anticorps forkhead box P2, anticorps lmw-gs, anticorps forkhead box transcription factor, anticorps forkhead box P2 L homeolog, anticorps FOXP2, anticorps Foxp2, anticorps foxp2, anticorps foxP2, anticorps foxp1c, anticorps foxp2.L

Sujet:

Description: This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.

Aliases: SPCH1, CAGH44, TNRC10, DKFZp686H1726

Poids moléculaire: 85 kDa

ID gène: 93986

HGNC: 93986