HDAC3 anticorps (AA 224-428)
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- Antigène Voir toutes HDAC3 Anticorps
- HDAC3 (Histone Deacetylase 3 (HDAC3))
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Épitope
- AA 224-428
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp HDAC3 est non-conjugé
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Application
- ELISA, Immunohistochemistry (IHC)
- Fonction
- HDAC3 Antibody
- Purification
- Ascitic fluid
- Immunogène
- Purified recombinant fragment of HDAC3 (aa224-428) expressed in E. Coli.
- Clone
- 3A7B5
- Isotype
- IgG1
- Top Product
- Discover our top product HDAC3 Anticorps primaire
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- Indications d'application
- ELISA: 1/10000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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HDAC3 overexpression and colon cancer cell proliferation and differentiation." dans: Molecular carcinogenesis, Vol. 47, Issue 2, pp. 137-47, (2008) (PubMed).
: "Histone deacetylase 3 interacts with and deacetylates myocyte enhancer factor 2." dans: Molecular and cellular biology, Vol. 27, Issue 4, pp. 1280-95, (2007) (PubMed).
: "Elevated and deregulated expression of HDAC3 in human astrocytic glial tumours." dans: Folia biologica, Vol. 52, Issue 1-2, pp. 21-33, (2006) (PubMed).
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HDAC3 overexpression and colon cancer cell proliferation and differentiation." dans: Molecular carcinogenesis, Vol. 47, Issue 2, pp. 137-47, (2008) (PubMed).
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- Antigène
- HDAC3 (Histone Deacetylase 3 (HDAC3))
- Autre désignation
- HDAC3 (HDAC3 Produits)
- Sujet
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Description: HDAC3: histone deacetylase 3, also known as HD3, RPD3, RPD3-2. Entrez Protein NC_000005. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
Aliases: HD3, RPD3, RPD3-2
- Poids moléculaire
- 48.8kDa
- ID gène
- 8841
- HGNC
- 8841
- UniProt
- O15379
- Pathways
- Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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