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HDAC3 anticorps (AA 224-428)

HDAC3 Reactivité: Humain ELISA, IHC Hôte: Souris Monoclonal 3A7B5 unconjugated
N° du produit ABIN969189
  • Antigène Voir toutes HDAC3 Anticorps
    HDAC3 (Histone Deacetylase 3 (HDAC3))
    Épitope
    • 18
    • 16
    • 16
    • 10
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 224-428
    Reactivité
    • 105
    • 65
    • 62
    • 8
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 80
    • 24
    • 1
    Souris
    Clonalité
    • 82
    • 23
    Monoclonal
    Conjugué
    • 61
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HDAC3 est non-conjugé
    Application
    • 91
    • 45
    • 32
    • 27
    • 27
    • 26
    • 16
    • 16
    • 13
    • 8
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC)
    Fonction
    HDAC3 Antibody
    Purification
    Ascitic fluid
    Immunogène
    Purified recombinant fragment of HDAC3 (aa224-428) expressed in E. Coli.
    Clone
    3A7B5
    Isotype
    IgG1
    Top Product
    Discover our top product HDAC3 Anticorps primaire
  • Indications d'application
    ELISA: 1/10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Spurling, Godman, Noonan, Rasmussen, Rosenberg, Giardina: "HDAC3 overexpression and colon cancer cell proliferation and differentiation." dans: Molecular carcinogenesis, Vol. 47, Issue 2, pp. 137-47, (2008) (PubMed).

    Grégoire, Xiao, Nie, Zhang, Xu, Li, Wong, Seto, Yang: "Histone deacetylase 3 interacts with and deacetylates myocyte enhancer factor 2." dans: Molecular and cellular biology, Vol. 27, Issue 4, pp. 1280-95, (2007) (PubMed).

    Libý, Kostrouchová, Pohludka, Yilma, Hrabal, Sikora, Brozová, Kostrouchová, Rall, Kostrouch: "Elevated and deregulated expression of HDAC3 in human astrocytic glial tumours." dans: Folia biologica, Vol. 52, Issue 1-2, pp. 21-33, (2006) (PubMed).

  • Antigène
    HDAC3 (Histone Deacetylase 3 (HDAC3))
    Autre désignation
    HDAC3 (HDAC3 Produits)
    Sujet

    Description: HDAC3: histone deacetylase 3, also known as HD3, RPD3, RPD3-2. Entrez Protein NC_000005. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.

    Aliases: HD3, RPD3, RPD3-2

    Poids moléculaire
    48.8kDa
    ID gène
    8841
    HGNC
    8841
    UniProt
    O15379
    Pathways
    Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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