Hexokinase 1 anticorps

N° du produit ABIN969194

Détail du produit anti-Hexokinase 1 anticorps

Antigène: Hexokinase 1 (HK1)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Hexokinase 1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Fonction: HK1 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human HK1 expressed in E. Coli.

Clone: 7A7

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-Hexokinase 1 (ABIN969194)

Martins-de-Souza, Gattaz, Schmitt, Rewerts, Marangoni, Novello, Maccarrone, Turck, Dias-Neto: "Alterations in oligodendrocyte proteins, calcium homeostasis and new potential markers in schizophrenia anterior temporal lobe are revealed by shotgun proteome analysis." dans: Journal of neural transmission (Vienna, Austria : 1996), Vol. 116, Issue 3, pp. 275-89, (2009) (PubMed).

Tsai: "Function of interdomain alpha-helix in human brain hexokinase: covalent linkage and catalytic regulation between N- and C-terminal halves." dans: Journal of biomedical science, Vol. 14, Issue 2, pp. 195-202, (2007) (PubMed).

Stelzl, Worm, Lalowski, Haenig, Brembeck, Goehler, Stroedicke, Zenkner, Schoenherr, Koeppen, Timm, Mintzlaff, Abraham, Bock, Kietzmann, Goedde, Toksöz, Droege, Krobitsch, Korn, Birchmeier, Lehrach et al.: "A human protein-protein interaction network: a resource for annotating the proteome. ..." dans: Cell, Vol. 122, Issue 6, pp. 957-68, (2005) (PubMed).

Détails sur Hexokinase 1

Antigène: Hexokinase 1 (HK1)

Autre désignation: HK1 (HK1 Produits)

Synonymes: anticorps HK1-ta, anticorps HK1-tb, anticorps HK1-tc, anticorps HKD, anticorps HKI, anticorps HMSNR, anticorps HXK1, anticorps Hexokinase, anticorps hk1, anticorps HEX, anticorps HEX-1, anticorps HK, anticorps ARABIDOPSIS THALIANA HEXOKINASE 1, anticorps ATHXK1, anticorps F19B15.160, anticorps F19B15_160, anticorps GIN2, anticorps GLUCOSE INSENSITIVE 2, anticorps HEXOKINASE, anticorps hexokinase 1, anticorps im:7148527, anticorps wu:fc09d08, anticorps wu:fc16e02, anticorps wu:fc21e02, anticorps wu:fq14b11, anticorps zgc:55790, anticorps zgc:77618, anticorps hexokinase-1, anticorps HK1, anticorps BB404130, anticorps Hk-1, anticorps Hk1-s, anticorps dea, anticorps mHk1-s, anticorps HEXOKIN, anticorps Hxk1, anticorps NtHxK1, anticorps NtHxk, anticorps hexokinase, anticorps StHK1, anticorps hxk, anticorps hk1-A, anticorps hexokinase 1, anticorps hexokinase-1, anticorps Hexokinase 1, anticorps hexokinase 1, putative, anticorps hexokinase 1 L homeolog, anticorps HK1, anticorps hk1, anticorps LOC100136279, anticorps Hex1, anticorps HXK1, anticorps Hk1, anticorps TA19800, anticorps hxk1, anticorps LOC107797523, anticorps LOC102604144, anticorps hk1.L

Sujet:

Description: The hexokinases utilize Mg-ATP as a phosphoryl donor to catalyze the first step of intracellular glucose metabolism, the conversion of glucose to glucose- 6-phosphate. Four hexokinase isoenzymes have been identified, including hexokinase I (HXK I), hexokinase II (HXK II), hexokinase III (HXK III) and hexokinase IV (HXK IV, also designated glucokinase or GCK). Hexokinases I-III each contain an N-terminal cluster of hydrophobic amino acids. Glucokinase lacks the N-terminal hydrophobic cluster. The hydrophobic cluster is thought to be necessary for membrane binding. This is substantiated by the finding that glucokinase has lower affinity for glucose than do the other hexokinases. HK I has been shown to be expressed in brain, kidney and heart tissues as well as in hepatoma cell lines.

Aliases: HKI, HXK1, HK1-ta, HK1-tb, HK1-tc, HK1

Poids moléculaire: 102kDa

ID gène: 3098

HGNC: 3098

UniProt: P19367

Pathways: Carbohydrate Homeostasis, L'effet Warburg