IGF2BP3 anticorps

N° du produit ABIN969208

Détail du produit anti-IGF2BP3 anticorps

Antigène: IGF2BP3 (Insulin-Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IGF2BP3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Fonction: IGF2BP3 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human IGF2BP3 expressed in E. Coli.

Clone: 8F11

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-IGF2BP3 (ABIN969208)

Sitnikova, Mendese, Liu, Woda, Lu, Dresser, Mohanty, Rock, Jiang: "IMP3 predicts aggressive superficial urothelial carcinoma of the bladder." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 14, Issue 6, pp. 1701-6, (2008) (PubMed).

Détails sur IGF2BP3

Antigène: IGF2BP3 (Insulin-Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3))

Autre désignation: IGF2BP3 (IGF2BP3 Produits)

Synonymes: anticorps CT98, anticorps IMP-3, anticorps IMP3, anticorps KOC1, anticorps VICKZ3, anticorps Ab2-255, anticorps RGD1306512, anticorps imp3, anticorps koc1, anticorps vera, anticorps imp-3, anticorps vg1rbp, anticorps vickz3, anticorps 2610101N11Rik, anticorps AA522010, anticorps AL022933, anticorps AU045931, anticorps Koc13, anticorps Neilsen, anticorps mimp3, anticorps dvr1rbp, anticorps wu:fb79c12, anticorps wu:fe06h09, anticorps zVg1RBP, anticorps B3, anticorps IGF2 mRNA-binding protein 3-B, anticorps IMP, anticorps IMP-3-B, anticorps Vg1 RBP-B, anticorps Vg1-RBP, anticorps igf2bp3, anticorps igf2bp3-a, anticorps igf2bp3-b, anticorps IGF2 mRNA-binding protein 3-A, anticorps IMP-3-A, anticorps Vg1 RBP-A, anticorps vera-A, anticorps insulin like growth factor 2 mRNA binding protein 3, anticorps insulin-like growth factor 2 mRNA binding protein 3, anticorps insulin like growth factor 2 mRNA binding protein 3 S homeolog, anticorps insulin like growth factor 2 mRNA binding protein 3 L homeolog, anticorps IGF2BP3, anticorps Igf2bp3, anticorps igf2bp3, anticorps igf2bp3.S, anticorps igf2bp3.L

Sujet:

Description: The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism.Tissue specificity: Expressed in fetal liver, fetal lung, fetal kidney, fetal thymus, fetal placenta, fetal follicles of ovary and gonocytes of testis, growing oocytes, spermatogonia and semen (at protein level). Expressed in cervix adenocarcinoma, in testicular, pancreatic and renal-cell carcinomas (at protein level). Expressed ubiquitously during fetal development at 8 and 14 weeks of gestation. Expressed in ovary, testis, brain, placenta, pancreatic cancer tissues and pancreatic cancer cell lines .IMP-3 is a marker for carcinomas and high-grade dysplastic lesions of pancreatic ductal epithelium.

Aliases: CT98, IMP3, KOC1, IMP-3, VICKZ3, DKFZp686F1078, IGF2BP3

Poids moléculaire: 69kDa

ID gène: 10643

HGNC: 10643

UniProt: O00425