Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

IL-2 anticorps

IL2 Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 8D5 unconjugated
N° du produit ABIN969214
  • Antigène Voir toutes IL-2 (IL2) Anticorps
    IL-2 (IL2) (Interleukin 2 (IL2))
    Reactivité
    • 150
    • 97
    • 43
    • 14
    • 9
    • 8
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 117
    • 81
    • 81
    • 12
    • 4
    • 2
    • 1
    Souris
    Clonalité
    • 164
    • 132
    • 1
    Monoclonal
    Conjugué
    • 152
    • 37
    • 23
    • 22
    • 18
    • 10
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IL-2 est non-conjugé
    Application
    • 164
    • 132
    • 88
    • 61
    • 43
    • 30
    • 28
    • 21
    • 14
    • 14
    • 13
    • 13
    • 13
    • 11
    • 11
    • 8
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purification
    purified
    Immunogène
    Purified recombinant fragment of IL2 expressed in E. coli.
    Clone
    8D5
    Isotype
    IgG1
    Top Product
    Discover our top product IL2 Anticorps primaire
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Das, Levine: "TGF-beta inhibits IL-2 production and promotes cell cycle arrest in TCR-activated effector/memory T cells in the presence of sustained TCR signal transduction." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 3, pp. 1490-8, (2008) (PubMed).

    Lesniewski, Haviernik, Weitzel, Kadereit, Kozik, Fanning, Yang, Hegerfeldt, Finney, Ratajczak, Greco, Paul, Maciejewski, Laughlin: "Regulation of IL-2 expression by transcription factor BACH2 in umbilical cord blood CD4+ T cells." dans: Leukemia, Vol. 22, Issue 12, pp. 2201-7, (2008) (PubMed).

  • Antigène
    IL-2 (IL2) (Interleukin 2 (IL2))
    Autre désignation
    IL-2 (IL2 Produits)
    Synonymes
    anticorps IL2, anticorps IL-2, anticorps il2, anticorps TCGF, anticorps lymphokine, anticorps Il-2, anticorps POIL2, anticorps interleukin 2, anticorps interleukin-15, anticorps IL2, anticorps il2, anticorps LOC100303688, anticorps Il2
    Sujet

    Description: IL-2: interleukin-2. Entrez Protein NP_000577. It is a 17.6 kDa secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.

    Aliases: Aldesleukin, TCGF, interleukin-2

    Poids moléculaire
    17.6 kDa
    ID gène
    3558
    HGNC
    3558
    Pathways
    Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
Vous êtes ici:
Support technique