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IL-2 anticorps

IL2 Reactivité: Humain ELISA Hôte: Souris Monoclonal 8D5 unconjugated
N° du produit ABIN969214
  • Antigène Voir toutes IL-2 (IL2) Anticorps
    IL-2 (IL2) (Interleukin 2 (IL2))
    Reactivité
    • 153
    • 96
    • 42
    • 15
    • 9
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
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    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 116
    • 83
    • 80
    • 11
    • 4
    • 2
    • 1
    Souris
    Clonalité
    • 167
    • 127
    • 1
    Monoclonal
    Conjugué
    • 153
    • 37
    • 24
    • 21
    • 17
    • 9
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IL-2 est non-conjugé
    Application
    • 161
    • 133
    • 89
    • 59
    • 42
    • 28
    • 28
    • 21
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    • 14
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    ELISA
    Fonction
    IL-2 Antibody
    Purification
    Ascitic fluid
    Immunogène
    Purified recombinant fragment of IL2 expressed in E. Coli.
    Clone
    8D5
    Isotype
    IgG1
    Top Product
    Discover our top product IL2 Anticorps primaire
  • Indications d'application
    ELISA: 1/10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Das, Levine: "TGF-beta inhibits IL-2 production and promotes cell cycle arrest in TCR-activated effector/memory T cells in the presence of sustained TCR signal transduction." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 3, pp. 1490-8, (2008) (PubMed).

    Lesniewski, Haviernik, Weitzel, Kadereit, Kozik, Fanning, Yang, Hegerfeldt, Finney, Ratajczak, Greco, Paul, Maciejewski, Laughlin: "Regulation of IL-2 expression by transcription factor BACH2 in umbilical cord blood CD4+ T cells." dans: Leukemia, Vol. 22, Issue 12, pp. 2201-7, (2008) (PubMed).

  • Antigène
    IL-2 (IL2) (Interleukin 2 (IL2))
    Autre désignation
    IL-2 (IL2 Produits)
    Sujet

    Description: IL-2: interleukin-2. Entrez Protein NP_000577. It is a 17.6 kDa secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.

    Aliases: Aldesleukin, TCGF, interleukin-2

    Poids moléculaire
    17.6kDa
    ID gène
    3558
    HGNC
    3558
    UniProt
    P60568
    Pathways
    Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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