IL-2 anticorps
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- Antigène Voir toutes IL-2 (IL2) Anticorps
- IL-2 (IL2) (Interleukin 2 (IL2))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp IL-2 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Purification
- purified
- Immunogène
- Purified recombinant fragment of IL2 expressed in E. coli.
- Clone
- 8D5
- Isotype
- IgG1
- Top Product
- Discover our top product IL2 Anticorps primaire
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- Indications d'application
- ELISA: 1:10000, WB: 1:500 - 1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- 4°C, -20°C for long term storage
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TGF-beta inhibits IL-2 production and promotes cell cycle arrest in TCR-activated effector/memory T cells in the presence of sustained TCR signal transduction." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 3, pp. 1490-8, (2008) (PubMed).
: "Regulation of IL-2 expression by transcription factor BACH2 in umbilical cord blood CD4+ T cells." dans: Leukemia, Vol. 22, Issue 12, pp. 2201-7, (2008) (PubMed).
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TGF-beta inhibits IL-2 production and promotes cell cycle arrest in TCR-activated effector/memory T cells in the presence of sustained TCR signal transduction." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 3, pp. 1490-8, (2008) (PubMed).
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- Antigène
- IL-2 (IL2) (Interleukin 2 (IL2))
- Autre désignation
- IL-2 (IL2 Produits)
- Synonymes
- anticorps IL2, anticorps IL-2, anticorps il2, anticorps TCGF, anticorps lymphokine, anticorps Il-2, anticorps POIL2, anticorps interleukin 2, anticorps interleukin-15, anticorps IL2, anticorps il2, anticorps LOC100303688, anticorps Il2
- Sujet
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Description: IL-2: interleukin-2. Entrez Protein NP_000577. It is a 17.6 kDa secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.
Aliases: Aldesleukin, TCGF, interleukin-2
- Poids moléculaire
- 17.6 kDa
- ID gène
- 3558
- HGNC
- 3558
- Pathways
- Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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