Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

Lamin A/C anticorps

LMNA Reactivité: Humain WB, IHC, ELISA Hôte: Souris Monoclonal 4E7 unconjugated
N° du produit ABIN969260
  • Antigène Voir toutes Lamin A/C (LMNA) Anticorps
    Lamin A/C (LMNA)
    Reactivité
    • 133
    • 75
    • 72
    • 27
    • 15
    • 14
    • 8
    • 7
    • 6
    • 6
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 98
    • 45
    • 2
    • 1
    Souris
    Clonalité
    • 97
    • 49
    Monoclonal
    Conjugué
    • 115
    • 9
    • 8
    • 6
    • 2
    • 2
    • 2
    • 2
    Cet anticorp Lamin A/C est non-conjugé
    Application
    • 120
    • 54
    • 53
    • 49
    • 32
    • 31
    • 30
    • 21
    • 15
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Fonction
    LMNA Antibody
    Purification
    Ascitic fluid
    Immunogène
    Purified recombinant fragment of human LMNA expressed in E. Coli.
    Clone
    4E7
    Isotype
    IgG1
    Top Product
    Discover our top product LMNA Anticorps primaire
  • Indications d'application
    ELISA: 1/10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Carboni, Porcu, Mura, Cocco, Marrosu, Maioli, Solla, Tranquilli, Orrù, Marrosu: "Evolution of the phenotype in a family with an LMNA gene mutation presenting with isolated cardiac involvement." dans: Muscle & nerve, Vol. 41, Issue 1, pp. 85-91, (2009) (PubMed).

  • Antigène
    Lamin A/C (LMNA)
    Autre désignation
    LMNA (LMNA Produits)
    Sujet

    Description: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Through alternate splicing, this gene encodes three type A lamin isoforms. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome.

    Aliases: FPL, IDC, LFP, CDDC, EMD2, FPLD, HGPS, LDP1, LMN1, LMNC, PRO1, CDCD1, CMD1A, FPLD2, LMNL1, CMT2B1

    Poids moléculaire
    74kDa
    ID gène
    4000
    HGNC
    4000
    UniProt
    P02545
    Pathways
    Apoptose, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus
Vous êtes ici:
Support technique