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LSD1 anticorps

KDM1A Reactivité: Humain WB, ELISA, IHC Hôte: Souris Monoclonal 1B2E5 unconjugated
N° du produit ABIN969264
  • Antigène Voir toutes LSD1 (KDM1A) Anticorps
    LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))
    Reactivité
    • 76
    • 36
    • 29
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 59
    • 15
    • 1
    Souris
    Clonalité
    • 59
    • 17
    Monoclonal
    Conjugué
    • 56
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp LSD1 est non-conjugé
    Application
    • 68
    • 35
    • 27
    • 21
    • 17
    • 13
    • 13
    • 10
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Fonction
    LSD1/AOF2 Antibody
    Purification
    Ascitic fluid
    Immunogène
    Purified recombinant fragment of human LSD1 expressed in E. Coli.
    Clone
    1B2E5
    Isotype
    IgG1
    Top Product
    Discover our top product KDM1A Anticorps primaire
  • Indications d'application
    ELISA: 1/10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Shi, Matson, Lan, Iwase, Baba, Shi: "Regulation of LSD1 histone demethylase activity by its associated factors." dans: Molecular cell, Vol. 19, Issue 6, pp. 857-64, (2005) (PubMed).

    Metzger, Wissmann, Yin, Müller, Schneider, Peters, Günther, Buettner, Schüle: "LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription." dans: Nature, Vol. 437, Issue 7057, pp. 436-9, (2005) (PubMed).

  • Antigène
    LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))
    Autre désignation
    LSD1/AOF2 (KDM1A Produits)
    Sujet

    Description: The amine oxidase domain 2 (AOF2) gene encodes a nuclear protein (LSD1, ~95 kDa) containing a Swirm domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. LSD1 is a chromatin-modifying enzyme, which serve as a docking module for the stabilization of the associated corepressor complex (es) on chromatin.

    Aliases: KDM1, LSD1, AOF2

    Poids moléculaire
    93kDa
    ID gène
    23028
    HGNC
    23028
    UniProt
    O60341
    Pathways
    Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Negative Regulation of intrinsic apoptotic Signaling, L'effet Warburg
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