MAP3K2 anticorps

N° du produit ABIN969272

Détail du produit anti-MAP3K2 anticorps

Antigène: MAP3K2 (Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MAP3K2 est non-conjugé

Application: ELISA, Immunocytochemistry (ICC)

Fonction: MAP3K2 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human MAP3K2 expressed in E. Coli.

Clone: 4B4

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-MAP3K2 (ABIN969272)

Kurada, Li, Mulherkar, Subramanian, Prasad, Prabhakar: "MADD, a splice variant of IG20, is indispensable for MAPK activation and protection against apoptosis upon tumor necrosis factor-alpha treatment." dans: The Journal of biological chemistry, Vol. 284, Issue 20, pp. 13533-41, (2009) (PubMed).

Cazares, Troyer, Mendrinos, Lance, Nyalwidhe, Beydoun, Clements, Drake, Semmes: "Imaging mass spectrometry of a specific fragment of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase kinase 2 discriminates cancer from uninvolved prostate tissue." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 17, pp. 5541-51, (2009) (PubMed).

Détails sur MAP3K2

Antigène: MAP3K2 (Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2))

Autre désignation: MAP3K2 (MAP3K2 Produits)

Synonymes: anticorps Mekk2, anticorps MEKK2, anticorps MEKK2B, anticorps 9630061B06Rik, anticorps AI585793, anticorps Mekk2b, anticorps mitogen activated protein kinase kinase kinase 2, anticorps mitogen-activated protein kinase kinase kinase 2, anticorps Map3k2, anticorps MAP3K2

Sujet:

Description: The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process.

Aliases: MEKK2, MEKK2B

Poids moléculaire: 70kDa

ID gène: 10746

HGNC: 10746

UniProt: Q9Y2U5

Pathways: Signalisation MAPK