NCOA3 anticorps (AA 1-200)

N° du produit ABIN969309

Détail du produit anti-NCOA3 anticorps

Antigène: NCOA3 (Nuclear Receptor Coactivator 3 (NCOA3))

Épitope: AA 1-200

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NCOA3 est non-conjugé

Application: ELISA

Fonction: NCOA3 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of NCOA3 (aa1-200) expressed in E. Coli.

Clone: 2C11B12

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-NCOA3 (ABIN969309)

Rangel, Torabian, Shaikh, Nosrati, Baehner, Haqq, Leong, Miller, Sagebiel, Kashani-Sabet: "Prognostic significance of nuclear receptor coactivator-3 overexpression in primary cutaneous melanoma." dans: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Vol. 24, Issue 28, pp. 4565-9, (2006) (PubMed).

Zheng, Wu, Smith, OMalley: "Rapid estrogen-induced phosphorylation of the SRC-3 coactivator occurs in an extranuclear complex containing estrogen receptor." dans: Molecular and cellular biology, Vol. 25, Issue 18, pp. 8273-84, (2005) (PubMed).

Détails sur NCOA3

Antigène: NCOA3 (Nuclear Receptor Coactivator 3 (NCOA3))

Autre désignation: NCOA3 (NCOA3 Produits)

Synonymes: anticorps NCOA3, anticorps ACTR, anticorps AIB-1, anticorps AIB1, anticorps CAGH16, anticorps CTG26, anticorps KAT13B, anticorps RAC3, anticorps SRC-3, anticorps SRC3, anticorps TNRC14, anticorps TNRC16, anticorps TRAM-1, anticorps bHLHe42, anticorps pCIP, anticorps 2010305B15Rik, anticorps AW321064, anticorps Actr, anticorps Aib1, anticorps Rac3, anticorps Src3, anticorps Tram-1, anticorps Tram1, anticorps p/Cip, anticorps pCip, anticorps actr, anticorps aib-1, anticorps aib1, anticorps cagh16, anticorps ctg26, anticorps kat13b, anticorps pcip, anticorps rac3, anticorps src-3, anticorps src3, anticorps tnrc14, anticorps tnrc16, anticorps tram-1, anticorps xSRC-3, anticorps nuclear receptor coactivator 3, anticorps nuclear receptor coactivator 3 S homeolog, anticorps NCOA3, anticorps Ncoa3, anticorps ncoa3.S

Sujet:

Description: NCOA3: nuclear receptor coactivator 3. The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Two transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein.

Aliases: ACTR, AIB1

ID gène: 8202

HGNC: 8202

UniProt: Q9Y6Q9

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha