CD73 anticorps
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- Antigène Voir toutes CD73 (NT5E) Anticorps
- CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD73 est non-conjugé
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Application
- Immunohistochemistry (IHC), ELISA
- Purification
- purified
- Immunogène
- Purified recombinant fragment of NT5E expressed in E. coli.
- Clone
- 1D7
- Isotype
- IgG1
- Top Product
- Discover our top product NT5E Anticorps primaire
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- Indications d'application
- ELISA: 1:10000, IHC: 1:200 - 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- 4°C, -20°C for long term storage
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Effects of ecto-5'-nucleotidase on human breast cancer cell growth in vitro and in vivo." dans: Oncology reports, Vol. 17, Issue 6, pp. 1341-6, (2007) (PubMed).
: "Extracellular adenine nucleotides metabolism in astrocyte cultures from different brain regions." dans: Neurochemistry international, Vol. 43, Issue 7, pp. 621-8, (2003) (PubMed).
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Effects of ecto-5'-nucleotidase on human breast cancer cell growth in vitro and in vivo." dans: Oncology reports, Vol. 17, Issue 6, pp. 1341-6, (2007) (PubMed).
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- Antigène
- CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))
- Autre désignation
- NT5E (NT5E Produits)
- Synonymes
- anticorps CALJA, anticorps CD73, anticorps E5NT, anticorps NT, anticorps NT5, anticorps NTE, anticorps eN, anticorps eNT, anticorps zgc:63784, anticorps NT5E, anticorps MGC114869, anticorps PSPTO2277, anticorps 2210401F01Rik, anticorps AI447961, anticorps Nt5, anticorps 5'-nucleotidase ecto, anticorps 5'-nucleotidase, ecto (CD73), anticorps 5'-nucleotidase, anticorps 5' nucleotidase, ecto, anticorps NT5E, anticorps nt5e, anticorps nt5e.S, anticorps PSPTO_2277, anticorps CBU_1233, anticorps MCA1322, anticorps Nt5e
- Sujet
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Description: 5'-nucleotidase, ecto (NT5E), also known as CD73 (Cluster of Differentiation 73). Ecto-5-prime-nucleotidase (5-prime-ribonucleotide phosphohydrolase, EC 3.1.3.5) catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP. The enzyme consists of a dimer of 2 identical 70-kD subunits bound by a glycosyl phosphatidyl inositol linkage to the external face of the plasma membrane. The enzyme is used as a marker of lymphocyte differentiation. Consequently, a deficiency of NT5 occurs in a variety of immunodeficiency diseases (e.g., see MIM 102700, MIM 300300). Other forms of 5-prime nucleotidase exist in the cytoplasm and lysosomes and can be distinguished from ecto-NT5 by their substrate affinities, requirement for divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate.
Aliases: eN, NT5, CD73
- Poids moléculaire
- 70 kDa
- ID gène
- 4907
- HGNC
- 4907
- Pathways
- Synaptic Membrane, Ribonucleoside Biosynthetic Process
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