OCT4 anticorps (AA 193-360)
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- Antigène Voir toutes OCT4 (POU5F1) Anticorps
- OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))
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Épitope
- AA 193-360
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp OCT4 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Purification
- purified
- Immunogène
- Purified recombinant fragment of Oct4 (aa193-360) expressed in E. coli.
- Clone
- 1D10H6
- Isotype
- IgG1
- Top Product
- Discover our top product POU5F1 Anticorps primaire
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- Indications d'application
- ELISA: 1:10000, WB: 1:500 - 1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- 4°C, -20°C for long term storage
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Isolation and characterization of a population of immature dental pulp stem cells expressing OCT-4 and other embryonic stem cell markers." dans: Cells, tissues, organs, Vol. 184, Issue 3-4, pp. 105-16, (2007) (PubMed).
: "OCT-4, an embryonic stem cell marker, is highly expressed in bladder cancer." dans: International journal of cancer. Journal international du cancer, Vol. 120, Issue 7, pp. 1598-602, (2007) (PubMed).
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Isolation and characterization of a population of immature dental pulp stem cells expressing OCT-4 and other embryonic stem cell markers." dans: Cells, tissues, organs, Vol. 184, Issue 3-4, pp. 105-16, (2007) (PubMed).
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- Antigène
- OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))
- Autre désignation
- Oct4 (POU5F1 Produits)
- Synonymes
- anticorps OCT3, anticorps OCT4, anticorps OTF-3, anticorps OTF3, anticorps OTF4, anticorps Oct-3, anticorps Oct-4, anticorps POU5F1, anticorps gp9, anticorps gp-9, anticorps oct4, anticorps pou2, anticorps POU-2, anticorps cb197, anticorps spg/pou2, anticorps chunp6868, anticorps wu:fd18d06, anticorps NF-A3, anticorps Oct-3/4, anticorps Oct3, anticorps Oct3/4, anticorps Oct4, anticorps Otf-3, anticorps Otf-4, anticorps Otf3, anticorps Otf3-rs7, anticorps Otf3g, anticorps Otf4, anticorps POU class 5 homeobox 1, anticorps POU domain, class 5, transcription factor 3, anticorps POU domain, class 5, transcription factor 1, anticorps POU5F1, anticorps pou5f3, anticorps Pou5f1
- Sujet
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Description: Oct4: octamer-binding transcription factor-4 (Oct-4, Otf-4) and Oct-3/4, also known as POU5F1(POU class 5 homeobox 1), octamerbinding transcription factor-3 (Oct-3, Otf-3), modulates embryonic stem (ES) cell populations by influencing lineage commitment. Entrez Protein NP_002692. Oct-3/4 sustains stem-cell selfrenewal and differentiation pathways. Transcription factors containing the POU homeodomain regulate tissue-specific gene expression in lymphoid and pituitary differentiation and in early mammalian development. Oct-3/4 is capable of inducing rapid proliferation and tumorigenic properties of ES cells through activation of the UTF1 gene. In humans, two Oct-3/4 isoforms contribute to influencing the undifferentiated phenotype of ES cells. Oct-3/4 pseudogenes localizing to human chromosomes 10 and 8 are reported to be transcribed in certain cancer cell lines and tissues.
Aliases: OCT3, OTF3, OTF4, MGC22487, POU5F1
- Poids moléculaire
- 38.5 kDa
- ID gène
- 5460
- HGNC
- 5460
- Pathways
- Stem Cell Maintenance
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