OCT4 anticorps
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- Antigène Voir toutes OCT4 (POU5F1) Anticorps
- OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp OCT4 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Immunogène
- Synthesized peptide of human Oct4.
- Clone
- 5F7
- Isotype
- IgG1
- Top Product
- Discover our top product POU5F1 Anticorps primaire
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- Indications d'application
- ELISA: 1:10000, WB: 1:500 - 1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- 4°C, -20°C for long term storage
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Esrrb activates Oct4 transcription and sustains self-renewal and pluripotency in embryonic stem cells." dans: The Journal of biological chemistry, Vol. 283, Issue 51, pp. 35825-33, (2008) (PubMed).
: "Epigenetic deregulation of the human Oct4 promoter in mouse cells." dans: Development genes and evolution, Vol. 218, Issue 10, pp. 561-6, (2008) (PubMed).
: "In vivo osteoprogenitor potency of human stromal cells from different tissues does not correlate with expression of POU5F1 or its pseudogenes." dans: Stem cells (Dayton, Ohio), Vol. 26, Issue 9, pp. 2419-24, (2008) (PubMed).
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Esrrb activates Oct4 transcription and sustains self-renewal and pluripotency in embryonic stem cells." dans: The Journal of biological chemistry, Vol. 283, Issue 51, pp. 35825-33, (2008) (PubMed).
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- Antigène
- OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))
- Autre désignation
- Oct4 (POU5F1 Produits)
- Synonymes
- anticorps OCT3, anticorps OCT4, anticorps OTF-3, anticorps OTF3, anticorps OTF4, anticorps Oct-3, anticorps Oct-4, anticorps POU5F1, anticorps gp9, anticorps gp-9, anticorps oct4, anticorps pou2, anticorps POU-2, anticorps cb197, anticorps spg/pou2, anticorps chunp6868, anticorps wu:fd18d06, anticorps NF-A3, anticorps Oct-3/4, anticorps Oct3, anticorps Oct3/4, anticorps Oct4, anticorps Otf-3, anticorps Otf-4, anticorps Otf3, anticorps Otf3-rs7, anticorps Otf3g, anticorps Otf4, anticorps POU class 5 homeobox 1, anticorps POU domain, class 5, transcription factor 3, anticorps POU domain, class 5, transcription factor 1, anticorps POU5F1, anticorps pou5f3, anticorps Pou5f1
- Sujet
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Description: This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6,22)(p21,q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. (provided by RefSeq).Tissue specificity: Expressed in developing brain. Highest levels found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum. Low levels of expression in adult tissues.
Aliases: OCT3, OCT4, OTF3, OTF4, OTF-3, Oct-3, Oct-4, MGC22487, POU5F1
- Poids moléculaire
- 45 kDa
- ID gène
- 5460
- HGNC
- 5460
- Pathways
- Stem Cell Maintenance
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