OLIG2 anticorps

N° du produit ABIN969331

Détail du produit anti-OLIG2 anticorps

Antigène: OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp OLIG2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Fonction: OLIG2 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human OLIG2 expressed in E. Coli.

Clone: 1G11

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-OLIG2 (ABIN969331)

Bonnet-Dupeyron, Combes, Boespflug-Tanguy, Vaurs-Barrière: "Absence of OLIG2 mutations in patients presenting with a severe Pelizaeus-Merzbacher-like leukodystrophy associated with motor neuron dysfunction." dans: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 147B, Issue 4, pp. 538-9, (2008) (PubMed).

Mikami, Hirose, Yoshida, Kawase, Ohnishi, Nagashima, Mukai, Okada, Ikeda: "Predominant expression of OLIG2 over ID2 in oligodendroglial tumors." dans: Virchows Archiv : an international journal of pathology, Vol. 450, Issue 5, pp. 575-84, (2007) (PubMed).

Détails sur OLIG2

Antigène: OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))

Autre désignation: OLIG2 (OLIG2 Produits)

Synonymes: anticorps olig3.2, anticorps MGC89336, anticorps OLIG2, anticorps BHLHB1, anticorps OLIGO2, anticorps PRKCBP2, anticorps RACK17, anticorps bHLHe19, anticorps wu:fc64g09, anticorps AI604895, anticorps Bhlhb1, anticorps Olg-2, anticorps Oligo2, anticorps RK17, anticorps oligodendrocyte transcription factor 4, anticorps oligodendrocyte transcription factor 2, anticorps oligodendrocyte lineage transcription factor 2, anticorps olig4, anticorps OLIG2, anticorps Olig2, anticorps olig2

Sujet:

Description: This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14,21)(q11.2,q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. Tissue specificity: Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable.

Aliases: BHLHB1, OLIGO2, RACK17, PRKCBP2, bHLHe19, OLIG2

Poids moléculaire: 32kDa

ID gène: 10215

HGNC: 10215

UniProt: Q13516