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PAK2 anticorps

PAK2 Reactivité: Humain, Singe WB, ELISA, IHC, ICC Hôte: Souris Monoclonal 3B5 unconjugated
N° du produit ABIN969338
  • Antigène Voir toutes PAK2 Anticorps
    PAK2 (P21-Activated Kinase 2 (PAK2))
    Reactivité
    • 89
    • 45
    • 43
    • 2
    • 2
    • 1
    Humain, Singe
    Hôte
    • 87
    • 3
    Souris
    Clonalité
    • 76
    • 14
    Monoclonal
    Conjugué
    • 57
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PAK2 est non-conjugé
    Application
    • 56
    • 45
    • 24
    • 17
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    Fonction
    PAK2 Antibody
    Purification
    Ascitic fluid
    Immunogène
    Purified recombinant fragment of PAK2 expressed in E. Coli.
    Clone
    3B5
    Isotype
    IgG1
    Top Product
    Discover our top product PAK2 Anticorps primaire
  • Indications d'application

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Machuy, Campa, Thieck, Rudel: "c-Abl-binding protein interacts with p21-activated kinase 2 (PAK-2) to regulate PDGF-induced membrane ruffles." dans: Journal of molecular biology, Vol. 370, Issue 4, pp. 620-32, (2007) (PubMed).

    Chu, Wu, Liao, Pardo, Zhao, Li, Mendenhall, Pali, Shen, Yu, Taylor, Aversa, Molineaux, Payan, Masuda: "A novel role for p21-activated protein kinase 2 in T cell activation." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 172, Issue 12, pp. 7324-34, (2004) (PubMed).

  • Antigène
    PAK2 (P21-Activated Kinase 2 (PAK2))
    Autre désignation
    PAK2 (PAK2 Produits)
    Sujet

    Description: PAK2, also known as P21 (CDKN1A)-activated kinase 2. The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. PAK2 is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. PAK2 has been shown to interact with SH3KBP1, CDC42 and Abl gene.

    Aliases: PAK65, PAKgamma

    Poids moléculaire
    61kDa
    ID gène
    5062
    HGNC
    5062
    UniProt
    Q13177
    Pathways
    Signalisation MAPK, Signalisation RTK, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
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