Prohibitin anticorps

N° du produit ABIN969353

Détail du produit anti-Prohibitin anticorps

Antigène: Prohibitin (PHB)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Prohibitin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Fonction: PHB Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human PHB expressed in E. Coli.

Clone: 5H7

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-Prohibitin (ABIN969353)

Shi, Li, Liu, Xu, Tang, Liang, Zhao, Yang: "Nuclear matrix protein, prohibitin, was down-regulated and translocated from nucleus to cytoplasm during the differentiation of osteosarcoma MG-63 cells induced by ginsenoside Rg1, cinnamic acid, and tanshinone IIA (RCT)." dans: Journal of cellular biochemistry, Vol. 108, Issue 4, pp. 926-34, (2009) (PubMed).

Ande, Mishra: "Prohibitin interacts with phosphatidylinositol 3,4,5-triphosphate (PIP3) and modulates insulin signaling." dans: Biochemical and biophysical research communications, Vol. 390, Issue 3, pp. 1023-8, (2009) (PubMed).

Détails sur Prohibitin

Antigène: Prohibitin (PHB)

Autre désignation: PHB (PHB Produits)

Synonymes: anticorps phb1, anticorps MGC75944, anticorps PHB, anticorps Phb, anticorps ACYPI000080, anticorps phb, anticorps PHB1, anticorps Bap32, anticorps sr:nyz128, anticorps wu:fa18f07, anticorps wu:fb09f05, anticorps prohibitin1, anticorps xphb1, anticorps prohibitin, anticorps prohibitin-2, anticorps prohibitin L homeolog, anticorps PHB, anticorps phb, anticorps LOC484431, anticorps LOC5576054, anticorps Phb, anticorps phb.L

Sujet:

Description: Prohibitin is an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.

Aliases: PHB1

Poids moléculaire: 30kDa

ID gène: 5245

HGNC: 5245

UniProt: P35232

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling