PPP1CA anticorps

N° du produit ABIN969359

Détail du produit anti-PPP1CA anticorps

Antigène: PPP1CA (Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PPP1CA est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: purified

Immunogène: Purified recombinant fragment of human PPP1A expressed in E. coli.

Clone: 6D1

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Références pour anticorps anti-PPP1CA (ABIN969359)

Luo, Peterson, Garcia, Coombs, Kofahl, Heinrich, Shabanowitz, Hunt, Yost, Virshup: "Protein phosphatase 1 regulates assembly and function of the beta-catenin degradation complex." dans: The EMBO journal, Vol. 26, Issue 6, pp. 1511-21, (2007) (PubMed).

Eto, Kirkbride, Elliott, Lo, Brautigan: "Association of the tensin N-terminal protein-tyrosine phosphatase domain with the alpha isoform of protein phosphatase-1 in focal adhesions." dans: The Journal of biological chemistry, Vol. 282, Issue 24, pp. 17806-15, (2007) (PubMed).

Détails sur PPP1CA

Antigène: PPP1CA (Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA))

Autre désignation: PPP1A (PPP1CA Produits)

Synonymes: anticorps PP-1A, anticorps PP1A, anticorps PP1alpha, anticorps PPP1A, anticorps Ppp1c, anticorps dism2, anticorps ppp1a, anticorps wu:fc04c08, anticorps wu:fc09b07, anticorps wu:fc30g11, anticorps wu:fe05h08, anticorps zgc:85729, anticorps Ppp1ca, anticorps fb18b03, anticorps fd20h04, anticorps wu:fb18b03, anticorps wu:fd20h04, anticorps wu:fl22a03, anticorps zgc:55744, anticorps zgc:76940, anticorps protein phosphatase 1 catalytic subunit alpha, anticorps protein phosphatase 1, catalytic subunit, alpha isoform, anticorps protein phosphatase 1, catalytic subunit, alpha isozyme L homeolog, anticorps protein phosphatase 1, catalytic subunit, alpha isozyme, anticorps protein phosphatase 1, catalytic subunit, alpha isozyme a, anticorps protein phosphatase 1, catalytic subunit, alpha isozyme b, anticorps PPP1CA, anticorps Ppp1ca, anticorps ppp1ca.L, anticorps ppp1ca, anticorps ppp1caa, anticorps ppp1cab

Sujet:

Description: The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Aliases: PP-1A, PPP1A, MGC1674, MGC15877, PP1alpha, PPP1CA

Poids moléculaire: 38 kDa

ID gène: 5499

HGNC: 5499

Pathways: M Phase, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Lipid Metabolism