PKN2 anticorps

N° du produit ABIN969363

Détail du produit anti-PKN2 anticorps

Antigène: PKN2 (Protein Kinase N2 (PKN2))

Reactivité: Humain, Souris, Rat, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PKN2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Purification: purified

Immunogène: Purified recombinant fragment of human PRK2 expressed in E. coli.

Clone: 1D1

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Références pour anticorps anti-PKN2 (ABIN969363)

Cornelis, Qi, Zhang, Kraft, Manson, Cai, Hunter, Hu: "Joint effects of common genetic variants on the risk for type 2 diabetes in U.S. men and women of European ancestry." dans: Annals of internal medicine, Vol. 150, Issue 8, pp. 541-50, (2009) (PubMed).

Détails sur PKN2

Antigène: PKN2 (Protein Kinase N2 (PKN2))

Autre désignation: PRK2 (PKN2 Produits)

Synonymes: anticorps PAK2, anticorps PRK2, anticorps PRKCL2, anticorps PRO2042, anticorps Pak-2, anticorps 6030436C20Rik, anticorps AI507382, anticorps Prkcl2, anticorps Stk7, anticorps pak2, anticorps prk2, anticorps pak-2, anticorps pro2042, anticorps PKN2, anticorps si:ch211-83f14.1, anticorps wu:fa97c07, anticorps protein kinase N2, anticorps protein kinase N2 L homeolog, anticorps PKN2, anticorps Pkn2, anticorps pkn2.L, anticorps pkn2

Sujet:

Description: Protein-kinase-C-related kinases (PRKs) are part of the lipid-regulated protein kinases (PKC) which also include liver PAK & PKN. Human PRK1 and PRK2 share structurally similar catalytic domains, but less similar N-terminal regulatory regions suggesting different regulatory domain functions. PRK1 and PRK2, as well as a third member of this family, PRK3, show distinct patterns of expression in adult tissues. Additionally, the serine-threonine kinase PRK2 can be specifically cleaved by caspase-3 (and/or caspase-3-like subfamily members) during apoptosis.

Aliases: PKN2, PAK2, PRK2, Pak-2, PRKCL2, PRO2042, MGC71074, MGC150606

Poids moléculaire: 140 kDa

ID gène: 5586

HGNC: 5586

Pathways: Cell-Cell Junction Organization