PRKAA1 anticorps
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- Antigène Voir toutes PRKAA1 Anticorps
- PRKAA1 (Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp PRKAA1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Fonction
- PRKAA1 Antibody
- Purification
- Ascitic fluid
- Immunogène
- Purified recombinant fragment of human PRKAA1 expressed in E. Coli.
- Clone
- 2B7
- Isotype
- IgG1
- Top Product
- Discover our top product PRKAA1 Anticorps primaire
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- Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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AMPK mediates curcumin-induced cell death in CaOV3 ovarian cancer cells." dans: Oncology reports, Vol. 20, Issue 6, pp. 1553-9, (2008) (PubMed).
: "Long-term forskolin stimulation induces AMPK activation and thereby enhances tight junction formation in human placental trophoblast BeWo cells." dans: Placenta, Vol. 29, Issue 12, pp. 1003-8, (2008) (PubMed).
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AMPK mediates curcumin-induced cell death in CaOV3 ovarian cancer cells." dans: Oncology reports, Vol. 20, Issue 6, pp. 1553-9, (2008) (PubMed).
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- Antigène
- PRKAA1 (Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))
- Autre désignation
- PRKAA1 (PRKAA1 Produits)
- Sujet
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Description: The protein belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Aliases: AMPK, AMPKa1, MGC33776, MGC57364, PRKAA1
- Poids moléculaire
- 64kDa
- ID gène
- 5562
- HGNC
- 5562
- UniProt
- Q13131
- Pathways
- AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, L'effet Warburg
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