RPS6KA3 anticorps

N° du produit ABIN969386

Détail du produit anti-RPS6KA3 anticorps

Antigène: RPS6KA3 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RPS6KA3 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Fonction: RSK2 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human RSK2 expressed in E. Coli.

Clone: 4E10

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-RPS6KA3 (ABIN969386)

Dehan, Bassermann, Guardavaccaro, Vasiliver-Shamis, Cohen, Lowes, Dustin, Huang, Taunton, Pagano: "betaTrCP- and Rsk1/2-mediated degradation of BimEL inhibits apoptosis." dans: Molecular cell, Vol. 33, Issue 1, pp. 109-16, (2009) (PubMed).

Cho, Yao, Pugliese, Malakhova, Bode, Dong: "A regulatory mechanism for RSK2 NH(2)-terminal kinase activity." dans: Cancer research, Vol. 69, Issue 10, pp. 4398-406, (2009) (PubMed).

Détails sur RPS6KA3

Antigène: RPS6KA3 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))

Autre désignation: RSK2 (RPS6KA3 Produits)

Synonymes: anticorps HU-1, anticorps MAPKAPK1A, anticorps RSK, anticorps RSK1, anticorps CLS, anticorps HU-3, anticorps ISPK-1, anticorps MAPKAPK1B, anticorps MRX19, anticorps RSK2, anticorps S6K-alpha3, anticorps p90-RSK2, anticorps pp90RSK2, anticorps MPK-9, anticorps Rsk2, anticorps RGD1563860, anticorps id:ibd1103, anticorps rps6ka3, anticorps si:ch211-114c12.12, anticorps wu:fk86e02, anticorps zgc:56006, anticorps zgc:158386, anticorps ribosomal protein S6 kinase A1, anticorps ribosomal protein S6 kinase A3, anticorps ribosomal protein S6 kinase polypeptide 3, anticorps ribosomal protein S6 kinase a, polypeptide 3a, anticorps ribosomal protein S6 kinase, polypeptide 3b, anticorps RPS6KA1, anticorps RPS6KA3, anticorps Rps6ka3, anticorps rps6ka3a, anticorps rps6ka3b

Sujet:

Description: This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS).

Aliases: RPS6KA3, CLS, RSK, HU-3, RSK2, MRX19, ISPK-1, p90-RSK2, pp90RSK2, MAPKAPK1B, S6K-alpha3

Poids moléculaire: 80kDa

ID gène: 6197

HGNC: 6197

UniProt: P51812

Pathways: Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades