Reticulon 3 anticorps

N° du produit ABIN969388

Détail du produit anti-Reticulon 3 anticorps

Antigène: Reticulon 3 (RTN3)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Reticulon 3 est non-conjugé

Application: ELISA, Immunocytochemistry (ICC)

Fonction: RTN3 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of RTN3 expressed in E. Coli.

Clone: 1E11

Isotype: IgG2a

Information d'application

Indications d'application:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-Reticulon 3 (ABIN969388)

Kim, Chai, Ryu: "Selenoprotein W as molecular target of methylmercury in human neuronal cells is down-regulated by GSH depletion." dans: Biochemical and biophysical research communications, Vol. 330, Issue 4, pp. 1095-102, (2005) (PubMed).

Cai, Saiyin, Lin, Zhang, Tang, Pan, Yu: "Identification of a new RTN3 transcript, RTN3-A1, and its distribution in adult mouse brain." dans: Brain research. Molecular brain research, Vol. 138, Issue 2, pp. 236-43, (2005) (PubMed).

Wakana, Koyama, Nakajima, Hatsuzawa, Nagahama, Tani, Hauri, Melançon, Tagaya: "Reticulon 3 is involved in membrane trafficking between the endoplasmic reticulum and Golgi." dans: Biochemical and biophysical research communications, Vol. 334, Issue 4, pp. 1198-205, (2005) (PubMed).

Oertle, Klinger, Stuermer, Schwab: "A reticular rhapsody: phylogenic evolution and nomenclature of the RTN/Nogo gene family." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 17, Issue 10, pp. 1238-47, (2003) (PubMed).

Détails sur Reticulon 3

Antigène: Reticulon 3 (RTN3)

Autre désignation: RTN3 (RTN3 Produits)

Synonymes: anticorps ASYIP, anticorps HAP, anticorps NSPL2, anticorps NSPLII, anticorps RTN3-A1, anticorps MGC56439, anticorps zgc:56439, anticorps zgc:77630, anticorps RTN3, anticorps hap, anticorps asyip, anticorps nspl2, anticorps xrtn3, anticorps nsplii, anticorps rtn3-a1, anticorps RTN3w, anticorps rtn3, anticorps XRTN3, anticorps rtn3-a, anticorps rtn3-b, anticorps reticulon 3, anticorps reticulon 3 L homeolog, anticorps reticulon-3, anticorps reticulon 3 S homeolog, anticorps RTN3, anticorps Rtn3, anticorps rtn3, anticorps rnt3, anticorps rtn3.L, anticorps LOC107131155, anticorps rtn3.S

Sujet:

Description: RTN3, reticulon 3. The reticulons are a group of highly conserved genes with preferential expression in neuroendocrine tissues. RTN3 may be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. There are 5 isoforms.

Aliases: HAP, ASYIP, NSPL2, NSPLII, RTN3-A1

Poids moléculaire: 113kDa

ID gène: 10313

HGNC: 10313

UniProt: O95197