SMAD5 anticorps

N° du produit ABIN969404

Détail du produit anti-SMAD5 anticorps

Antigène: SMAD5 (SMAD, Mothers Against DPP Homolog 5 (SMAD5))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SMAD5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Fonction: SMAD5 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human SMAD5 expressed in E. Coli.

Clone: 3H9

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-SMAD5 (ABIN969404)

Chang, Chang, Lee, Lee, Yeh, Yeh, Cheng, Chien, Chiu: "Tumor cell cycle arrest induced by shear stress: Roles of integrins and Smad." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 10, pp. 3927-32, (2008) (PubMed).

Monzen, Ito, Naito, Kasai, Hiroi, Hayashi, Shiojima, Yamazaki, Miyazono, Asashima, Nagai, Komuro: "A crucial role of a high mobility group protein HMGA2 in cardiogenesis." dans: Nature cell biology, Vol. 10, Issue 5, pp. 567-74, (2008) (PubMed).

Détails sur SMAD5

Antigène: SMAD5 (SMAD, Mothers Against DPP Homolog 5 (SMAD5))

Autre désignation: SMAD5 (SMAD5 Produits)

Synonymes: anticorps DWFC, anticorps JV5-1, anticorps MADH5, anticorps Madh5, anticorps SBN, anticorps fb67b04, anticorps mad, anticorps madh5, anticorps sb:cb400, anticorps smd5, anticorps wu:fb67b04, anticorps SMAD5, anticorps DKFZp468M0619, anticorps 1110051M15Rik, anticorps AI451355, anticorps Dwf-C, anticorps MusMLP, anticorps SMAD family member 5, anticorps SMAD5, anticorps Smad5, anticorps smad5

Sujet:

Description: Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD). SMAD5 is required for normal development of the cardiovascular system in vivo, lack of the SMAD5 gene results in apoptosis of cardiac myocytes. 3 Upregulation of SMAD5 has been reported to mediate apoptosis of gastric epithelial cells induced by Helicobacter pylori infection. Tissue specificity: Ubiquitous.

Aliases: Dwfc, JV5-1, MADH5, DKFZp781C1895, DKFZp781O1323, SMAD5

Poids moléculaire: 52kDa

ID gène: 4090

HGNC: 4090

UniProt: Q99717