STAT6 anticorps
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- Antigène Voir toutes STAT6 Anticorps
- STAT6 (Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6))
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Reactivité
- Humain, Souris, Rat, Singe
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp STAT6 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
- Purification
- purified
- Immunogène
- Purified recombinant fragment of human STAT6 expressed in E. coli.
- Clone
- 7D3
- Isotype
- IgG1
- Top Product
- Discover our top product STAT6 Anticorps primaire
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- Indications d'application
- ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- 4°C, -20°C for long term storage
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Polymorphisms in interleukin-4-related genes in patients with minimal change nephrotic syndrome." dans: Pediatric nephrology (Berlin, Germany), Vol. 24, Issue 3, pp. 489-95, (2009) (PubMed).
: "IL-4 alters expression patterns of storage components of vascular endothelial cell-specific granules through STAT6- and SOCS-1-dependent mechanisms." dans: Molecular immunology, Vol. 46, Issue 10, pp. 2080-9, (2009) (PubMed).
: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." dans: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).
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Polymorphisms in interleukin-4-related genes in patients with minimal change nephrotic syndrome." dans: Pediatric nephrology (Berlin, Germany), Vol. 24, Issue 3, pp. 489-95, (2009) (PubMed).
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- Antigène
- STAT6 (Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6))
- Autre désignation
- STAT6 (STAT6 Produits)
- Synonymes
- anticorps D12S1644, anticorps IL-4-STAT, anticorps STAT6B, anticorps STAT6C, anticorps signal transducer and activator of transcription 6, anticorps signal transducer and activator of transcription 6-like, anticorps STAT6, anticorps Stat6, anticorps LOC100859543
- Sujet
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Description: STAT6 protein is a transcription factor activated by cytokines, particularly interleukin 4 and IL 13. (STAT6-/-) were found to be deficient in IL 4 mediated functions including Th2 helper T cell differentiation, expression of cell surface markers, T cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL 4 mediated proliferation. STAT6 mRNA has been detected in peripheral bloodlymphocytes, colon, intestine, ovary, prostate,thymus, spleen, kidney, liver, lung and placenta. STAT6 is critically involved in Th2 immune response.
Aliases: STAT6B, STAT6C, D12S1644, IL-4-STAT, STAT6
- Poids moléculaire
- 94 kDa
- ID gène
- 6778
- HGNC
- 6778
- Pathways
- Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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