Osteoprotegerin anticorps
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- Antigène Voir toutes Osteoprotegerin (TNFRSF11B) Anticorps
- Osteoprotegerin (TNFRSF11B) (Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Osteoprotegerin est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Purification
- purified
- Immunogène
- Purified recombinant fragment of human TNFRSF11B expressed in E. coli.
- Clone
- 5A11
- Isotype
- IgG1
- Top Product
- Discover our top product TNFRSF11B Anticorps primaire
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- Indications d'application
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- 4°C, -20°C for long term storage
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A single-nucleotide polymorphism in the gene encoding osteoprotegerin is associated with diastolic blood pressure in older men." dans: American journal of hypertension, Vol. 22, Issue 11, pp. 1167-70, (2009) (PubMed).
: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." dans: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).
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A single-nucleotide polymorphism in the gene encoding osteoprotegerin is associated with diastolic blood pressure in older men." dans: American journal of hypertension, Vol. 22, Issue 11, pp. 1167-70, (2009) (PubMed).
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- Antigène
- Osteoprotegerin (TNFRSF11B) (Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))
- Autre désignation
- TNFRSF11B (TNFRSF11B Produits)
- Synonymes
- anticorps CD254, anticorps ODF, anticorps OPGL, anticorps OPTB2, anticorps RANKL, anticorps TRANCE, anticorps hRANKL2, anticorps sOdf, anticorps OCIF, anticorps OPG, anticorps TR1, anticorps Opg, anticorps ocif, anticorps opg, anticorps tr1, anticorps TNF superfamily member 11, anticorps TNF receptor superfamily member 11b, anticorps tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin), anticorps TNF receptor superfamily member 11B, anticorps tumor necrosis factor receptor superfamily member 11b S homeolog, anticorps tumor necrosis factor receptor superfamily, member 11b, anticorps TNFSF11, anticorps TNFRSF11B, anticorps Tnfrsf11b, anticorps tnfrsf11b.S
- Classe de substances
- Chemical
- Sujet
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Description: The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.
Aliases: OPG, TR1, OCIF, MGC29565, TNFRSF11B
- Poids moléculaire
- 60 kDa
- ID gène
- 4982
- HGNC
- 4982
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