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TNNI2 anticorps

TNNI2 Reactivité: Humain ELISA, IHC, FACS Hôte: Souris Monoclonal 2F12A11 unconjugated
N° du produit ABIN969441
  • Antigène Voir toutes TNNI2 Anticorps
    TNNI2 (Fast Skeletal Troponin I (TNNI2))
    Reactivité
    • 35
    • 18
    • 8
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 26
    • 16
    • 2
    Souris
    Clonalité
    • 26
    • 18
    Monoclonal
    Conjugué
    • 29
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TNNI2 est non-conjugé
    Application
    • 35
    • 17
    • 15
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
    Fonction
    TNNI2 Antibody
    Purification
    Ascitic fluid
    Immunogène
    Purified recombinant fragment of human TNNI2 expressed in E. Coli.
    Clone
    2F12A11
    Isotype
    IgG1
  • Indications d'application

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." dans: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).

    Moran, Garriock, Miller, Heimark, Gregorio, Krieg: "Expression of the fast twitch troponin complex, fTnT, fTnI and fTnC, in vascular smooth muscle." dans: Cell motility and the cytoskeleton, Vol. 65, Issue 8, pp. 652-61, (2008) (PubMed).

  • Antigène
    TNNI2 (Fast Skeletal Troponin I (TNNI2))
    Autre désignation
    TNNI2 (TNNI2 Produits)
    Sujet

    Description: This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene.

    Aliases: DA2B, FSSV, fsTnI, AMCD2B

    Poids moléculaire
    21kDa
    ID gène
    7136
    HGNC
    7136
    UniProt
    P48788
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