TYK2 anticorps
(2 références)-
- Antigène Voir toutes TYK2 Anticorps
- TYK2 (Tyrosine Kinase 2 (TYK2))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp TYK2 est non-conjugé
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Application
- ELISA
- Fonction
- Tyk2 Antibody
- Purification
- Ascitic fluid
- Immunogène
- Purified recombinant fragment of Tyk2 expressed in E. Coli.
- Clone
- 8G8B3
- Isotype
- IgG1
- Top Product
- Discover our top product TYK2 Anticorps primaire
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anti-Tyrosine Kinase 2 (TYK2) (AA 276-375) antibody
TYK2 Reactivité: Humain WB, ELISA, IF, IHC (p), IP Hôte: Souris Monoclonal 6G12 unconjugated
anti-Tyrosine Kinase 2 (TYK2) (AA 276-375) antibodyTYK2 Reactivité: Humain WB, ELISA, IHC (p) Hôte: Souris Monoclonal 6H1 unconjugated
anti-Tyrosine Kinase 2 (TYK2) (AA 750-850) antibodyTYK2 Reactivité: Humain WB, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Tyrosine Kinase 2 (TYK2) (pTyr1054), (pTyr1055) antibodyTYK2 Reactivité: Humain, Souris, Rat WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Tyrosine Kinase 2 (TYK2) (AA 286-372) antibodyTYK2 Reactivité: Humain ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Tyrosine Kinase 2 (TYK2) (AA 1-1187) antibodyTYK2 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
anti-Tyrosine Kinase 2 (TYK2) antibodyTYK2 Reactivité: Humain WB, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Tyrosine Kinase 2 (TYK2) (C-Term) antibodyTYK2 Reactivité: Humain, Souris, Rat WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Tyrosine Kinase 2 (TYK2) (AA 1020-1069) antibodyTYK2 Reactivité: Humain, Souris WB, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Tyrosine Kinase 2 (TYK2) (AA 915-1173) antibodyTYK2 Reactivité: Humain WB, ELISA, IHC (p), ICC, IHC (fro) Hôte: Lapin Polyclonal unconjugated
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- Indications d'application
- ELISA: 1/10000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Tyk2 negatively regulates adaptive Th1 immunity by mediating IL-10 signaling and promoting IFN-gamma-dependent IL-10 reactivation." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 176, Issue 12, pp. 7263-71, (2006) (PubMed).
: "Enhanced Th2 cell-mediated allergic inflammation in Tyk2-deficient mice." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 2, pp. 1077-83, (2003) (PubMed).
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: "Tyk2 negatively regulates adaptive Th1 immunity by mediating IL-10 signaling and promoting IFN-gamma-dependent IL-10 reactivation." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 176, Issue 12, pp. 7263-71, (2006) (PubMed).
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- Antigène
- TYK2 (Tyrosine Kinase 2 (TYK2))
- Autre désignation
- Tyk2 (TYK2 Produits)
- Synonymes
- anticorps JTK1, anticorps tyrosine kinase 2, anticorps TYK2, anticorps Tyk2
- Sujet
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Description: Tyk2 (tyrosine kinase 2),with 1187-amino acid protein (about 131 kDa), belongs to the family of non-receptor janus tyrosine kinases, which also includes Jak1, Jak2, and Jak3. Kinases of the Jak family regulate a spectrum of cellular functions downstream of activated cytokine receptors in the lympho-hematopoietic system. Tyk2 is activated by a variety of cytokines: IFN-alpha, IFN-beta, IL-6, IL-10, IL-12, and IL-13 and promotes IFN-gamma production by Th1-type CD4 cells. Tyk2 can be viewed as a dual-function Jak, mediating both pro-inflammatory and anti-inflammatory cytokine responses. Tyk2 is also an important regulator of lymphoid tumor surveillance.
Aliases: JTK1
- ID gène
- 7297
- HGNC
- 7297
- UniProt
- P29597
- Pathways
- Signalistation JAK/STAT, Hepatitis C
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