WDR5 anticorps

N° du produit ABIN969456

Détail du produit anti-WDR5 anticorps

Antigène: WDR5 (WD Repeat Domain 5 (WDR5))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp WDR5 est non-conjugé

Application: Western Blotting (WB), ELISA

Fonction: WDR5 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human WDR5 expressed in E. Coli.

Clone: 7B11

Isotype: IgG2b

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-WDR5 (ABIN969456)

Patel, Vought, Dharmarajan, Cosgrove: "A conserved arginine-containing motif crucial for the assembly and enzymatic activity of the mixed lineage leukemia protein-1 core complex." dans: The Journal of biological chemistry, Vol. 283, Issue 47, pp. 32162-75, (2008) (PubMed).

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." dans: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Détails sur WDR5

Antigène: WDR5 (WD Repeat Domain 5 (WDR5))

Autre désignation: WDR5 (WDR5 Produits)

Synonymes: anticorps BIG-3, anticorps SWD3, anticorps 2410008O07Rik, anticorps AA408785, anticorps AA960360, anticorps Big, anticorps Big-3, anticorps zgc:56591, anticorps zgc:76895, anticorps wu:fk47f04, anticorps wdr5-a, anticorps MGC80538, anticorps wdr5-b, anticorps MGC81485, anticorps big-3, anticorps swd3, anticorps xwdr5, anticorps WDR5B, anticorps WD repeat domain 5, anticorps WD repeat domain 5 L homeolog, anticorps WD repeat domain 5 S homeolog, anticorps WDR5, anticorps Wdr5, anticorps wdr5, anticorps wdr5.L, anticorps wdr5.S

Sujet:

Description: WD-repeat protein 5 (WDR5, also designated BMP-2-induced gene 3 kb or BIG-3) belongs to the family of WD-40 repeat proteins, and is essential for vertebrate development, Hox gene activation and global H3K4 trimethylation. WDR5 is a conserved subunit of Trithorax (TRX) histone methyltransferase complexes that selectively binds to dimethylated Lys4 (K4me2) in Histone H3 to promote K4 trimethylation by TRX. It is expressed in osteoblasts, chondrocytes, osteocytes and marrow stromal cells. The WDR5 protein contains 7 WD-repeats, which may play a role in its function of accelerating osteoblast differentiation.

Aliases: SWD3, BIG-3, WDR5

Poids moléculaire: 36.6kDa

ID gène: 11091

HGNC: 11091

UniProt: P61964