Inhibin alpha anticorps

N° du produit ABIN969483

Détail du produit anti-Inhibin alpha anticorps

Antigène: Inhibin alpha (INHA) (Inhibin, alpha (INHA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Inhibin alpha est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Fonction: INHA (Inhibin alpha) Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human INHA expressed in E. Coli.

Clone: 4A2

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur Inhibin alpha

Antigène: Inhibin alpha (INHA) (Inhibin, alpha (INHA))

Autre désignation: INHA (Inhibin alpha) (INHA Produits)

Synonymes: anticorps si:dkey-91f15.2, anticorps INHA, anticorps MGC108500, anticorps AW555078, anticorps inhibin, alpha, anticorps inhibin alpha subunit, anticorps inhibin alpha, anticorps inhibin alpha L homeolog, anticorps inha, anticorps INHA, anticorps inha.L, anticorps Inha

Sujet:

Description: INHA (A-inhibin subunit precursor, inhibin alpha subunit ), also called inhibin (alpha) ,which is located on chromosome 2q33-q36. Inhibin is a gonadal protein that preferentially suppresses the secretion of pituitary follicle-stimulating hormone (FSH). Inhibin comprises of two subunits,Inhibin A and B. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa cell tumors and can therefore be used as a marker for primary as well as recurrent disease. In addition to their role in endocrine feedback in the reproductive sytem, inhibins subserve local regulatory roles in numerous extragonadal tissues, including brain, adrenal,bone marrow, placenta, and most notably anterior pituitary. Inhibin alpha subunit gene expression is down regulated in human prostate cancer, suggesting a tumor suppressive role.

Aliases: INHA, inhibin, alpha

Poids moléculaire: 40kDa

ID gène: 3623

HGNC: 3623

UniProt: P05111

Pathways: Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion