NK2 Homeobox 5 anticorps

N° du produit ABIN969487

Détail du produit anti-NK2 Homeobox 5 anticorps

Antigène: NK2 Homeobox 5 (NKX2-5)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NK2 Homeobox 5 est non-conjugé

Application: ELISA

Fonction: NKX2.5 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human NKX2.5 expressed in E. Coli.

Clone: 2E1

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-NK2 Homeobox 5 (ABIN969487)

Brewer, Alexandrovich, Mjaatvedt, Shah, Patient, Pizzey: "GATA factors lie upstream of Nkx 2.5 in the transcriptional regulatory cascade that effects cardiogenesis." dans: Stem cells and development, Vol. 14, Issue 4, pp. 425-39, (2005) (PubMed).

Ikeda, Hiroi, Hosoda, Utsunomiya, Matsuo, Ito, Inoue, Sumiyoshi, Takano, Nagai, Komuro: "Novel point mutation in the cardiac transcription factor CSX/NKX2.5 associated with congenital heart disease." dans: Circulation journal : official journal of the Japanese Circulation Society, Vol. 66, Issue 6, pp. 561-3, (2002) (PubMed).

Détails sur NK2 Homeobox 5

Antigène: NK2 Homeobox 5 (NKX2-5)

Autre désignation: NKX2.5 (NKX2-5 Produits)

Synonymes: anticorps CHNG5, anticorps CSX, anticorps CSX1, anticorps HLHS2, anticorps NKX2.5, anticorps NKX2E, anticorps NKX4-1, anticorps VSD3, anticorps Csx, anticorps Nkx-2.5, anticorps Nkx2.5, anticorps tinman, anticorps nk2.5, anticorps nkx2-5, anticorps zgc:111912, anticorps AR2, anticorps XNkx2-5, anticorps csx, anticorps nkx-2.5, anticorps nkx2-5b, anticorps nkx2.5, anticorps NKX2-5, anticorps Nkx2-5, anticorps csx1, anticorps nkx2e, anticorps XNkx-2.5, anticorps CNKX-2.5, anticorps NKX-2.5, anticorps NK2 homeobox 5, anticorps NK2 homeobox 5 S homeolog, anticorps NKX2-5, anticorps Nkx2-5, anticorps nkx2.5, anticorps nkx2-5.S, anticorps nkx2-5

Sujet:

Description: NKX2.5: NK2 transcription factor related, locus 5 (Drosophila), also known as CSX. It is a homeobox-containing transcription factor. This transcription factor functions in heart formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants.

Aliases: CSX, NKX2E

Poids moléculaire: 35kDa

ID gène: 1482

HGNC: 1482

UniProt: P52952

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development