MATK anticorps

N° du produit ABIN969495

Détail du produit anti-MATK anticorps

Antigène: MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MATK est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Fonction: MATK Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human MATK expressed in E. Coli.

Clone: 9D7

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-MATK (ABIN969495)

McShan, Zagozdzon, Park, Zrihan-Licht, Fu, Avraham, Avraham: "Csk homologous kinase associates with RAFTK/Pyk2 in breast cancer cells and negatively regulates its activation and breast cancer cell migration." dans: International journal of oncology, Vol. 21, Issue 1, pp. 197-205, (2002) (PubMed).

Détails sur MATK

Antigène: MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))

Autre désignation: MATK (MATK Produits)

Synonymes: anticorps si:ch211-63j24.2, anticorps CHK, anticorps CTK, anticorps HHYLTK, anticorps HYL, anticorps HYLTK, anticorps Lsk, anticorps Ntk, anticorps Batk, anticorps megakaryocyte-associated tyrosine kinase, anticorps zinc finger RNA binding protein 2, anticorps matk, anticorps MATK, anticorps Matk, anticorps ZFR2

Sujet:

Description: MATK (megakaryocyte-associated tyrosine kinase), also known as CTK, this protein has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer.

Aliases: CHK, CTK

Poids moléculaire: 56kDa

ID gène: 4145

HGNC: 4145

UniProt: P42679