EIF4B anticorps

N° du produit ABIN969517

Détail du produit anti-EIF4B anticorps

Antigène: EIF4B (Eukaryotic Translation Initiation Factor 4B (EIF4B))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp EIF4B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Fonction: EIF4B Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human EIF4B expressed in E. Coli.

Clone: 1F5

Isotype: IgG2b

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-EIF4B (ABIN969517)

Mokas, Mills, Garreau, Fournier, Robert, Arya, Kaufman, Pelletier, Mazroui: "Uncoupling stress granule assembly and translation initiation inhibition." dans: Molecular biology of the cell, Vol. 20, Issue 11, pp. 2673-83, (2009) (PubMed).

Shahbazian, Roux, Mieulet, Cohen, Raught, Taunton, Hershey, Blenis, Pende, Sonenberg: "The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity." dans: The EMBO journal, Vol. 25, Issue 12, pp. 2781-91, (2006) (PubMed).

Détails sur EIF4B

Antigène: EIF4B (Eukaryotic Translation Initiation Factor 4B (EIF4B))

Autre désignation: EIF4B (EIF4B Produits)

Synonymes: anticorps EIF-4B, anticorps PRO1843, anticorps CG10837, anticorps Dm-eIF4B, anticorps Dmel\\CG10837, anticorps Eif4B, anticorps eIF-4B-L, anticorps eIF-4B-S, anticorps eIF-4b, anticorps eIF4B, anticorps eIF4B-L, anticorps eIF4B-S, anticorps eIf4b, anticorps 2310046H11Rik, anticorps AL024095, anticorps C85189, anticorps Eif4a2, anticorps eif4b, anticorps fb15c09, anticorps wu:fb15c09, anticorps zgc:101532, anticorps MGC89384, anticorps eukaryotic translation initiation factor 4B, anticorps eukaryotic initiation factor 4B, anticorps Eukaryotic initiation factor 4B, anticorps eukaryotic translation initiation factor 4Bb, anticorps eukaryotic translation initiation factor 4Ba, anticorps eukaryotic translation initiation factor 4B S homeolog, anticorps EIF4B, anticorps Eif4B, anticorps eIF-4B, anticorps Eif4b, anticorps eif4bb, anticorps eif4b, anticorps eif4ba, anticorps eif4b.S, anticorps LOC100284982, anticorps LOC100380867

Sujet:

Description: The eukaryotic translation initiation factor 4B (eIF4B) plays a critical role in recruiting the 40S ribosomal subunit to the mRNA.It functions in close association with eIF4F and eIF4A. It binds near the 5'-terminal cap of mRNA in the presence of eIF4F and ATP. It promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both eIF4A and eIF4F

Aliases: EIF-4B, PRO1843

Poids moléculaire: 80kDa

ID gène: 1975

HGNC: 1975

UniProt: P23588