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MELK anticorps (AA 637-651)

MELK Reactivité: Humain ELISA, IHC, ICC, FACS Hôte: Souris Monoclonal 2G2 unconjugated
N° du produit ABIN969538
  • Antigène Voir toutes MELK Anticorps
    MELK (Maternal Embryonic Leucine Zipper Kinase (MELK))
    Épitope
    • 15
    • 8
    • 8
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 637-651
    Reactivité
    • 61
    • 18
    • 14
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    Humain
    Hôte
    • 61
    • 4
    • 1
    Souris
    Clonalité
    • 61
    • 5
    Monoclonal
    Conjugué
    • 35
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MELK est non-conjugé
    Application
    • 39
    • 28
    • 13
    • 13
    • 7
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)
    Fonction
    MELK Antibody
    Séquence
    VYKRLVEDIL SSCKV
    Purification
    Purified antibody
    Immunogène
    Synthesized peptide of human MELK(AA: 637-651:C-VYKRLVEDILSSCKV).
    Clone
    2G2
    Isotype
    IgG2a
  • Indications d'application

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Nakano, Joshi, Visnyei, Hu, Watanabe, Lam, Wexler, Saigusa, Nakamura, Laks, Mischel, Viapiano, Kornblum: "Siomycin A targets brain tumor stem cells partially through a MELK-mediated pathway." dans: Neuro-oncology, Vol. 13, Issue 6, pp. 622-34, (2011) (PubMed).

    Pickard, Green, Ellis, Caldas, Hedge, Mourtada-Maarabouni, Williams: "Dysregulated expression of Fau and MELK is associated with poor prognosis in breast cancer." dans: Breast cancer research : BCR, Vol. 11, Issue 4, pp. R60, (2009) (PubMed).

  • Antigène
    MELK (Maternal Embryonic Leucine Zipper Kinase (MELK))
    Autre désignation
    MELK (MELK Produits)
    Synonymes
    anticorps MELK, anticorps xmelk, anticorps Melk, anticorps HPK38, anticorps AI327312, anticorps MPK38, anticorps mKIAA0175, anticorps fb71b01, anticorps fe01f04, anticorps wu:fb71b01, anticorps wu:fe01f04, anticorps maternal embryonic leucine zipper kinase, anticorps maternal embryonic leucine zipper kinase L homeolog, anticorps MELK, anticorps melk, anticorps cgd5_2270, anticorps Melk, anticorps melk.L
    Sujet

    Description: Maternal embryonic leucine-zipper kinase (MELK) is a key regulator of survival of stemlike GBM cells in vitro. MELK expression is increased in breast cancer tissue and this increase is also associated with poor patient survival, as predicted for a candidate oncogene.

    Aliases: HPK38

    Poids moléculaire
    74.6kDa
    ID gène
    9833
    HGNC
    9833
    UniProt
    Q14680
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