MELK anticorps (AA 637-651)
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- Antigène Voir toutes MELK Anticorps
- MELK (Maternal Embryonic Leucine Zipper Kinase (MELK))
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Épitope
- AA 637-651
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp MELK est non-conjugé
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Application
- ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)
- Séquence
- VYKRLVEDIL SSCKV
- Immunogène
- Synthesized peptide of human MELK(AA: 637-651:C-VYKRLVEDILSSCKV).
- Clone
- 2G2
- Isotype
- IgG2a
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- Indications d'application
- ELISA: 1:10000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- 4°C, -20°C for long term storage
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Siomycin A targets brain tumor stem cells partially through a MELK-mediated pathway." dans: Neuro-oncology, Vol. 13, Issue 6, pp. 622-34, (2011) (PubMed).
: "Dysregulated expression of Fau and MELK is associated with poor prognosis in breast cancer." dans: Breast cancer research : BCR, Vol. 11, Issue 4, pp. R60, (2009) (PubMed).
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Siomycin A targets brain tumor stem cells partially through a MELK-mediated pathway." dans: Neuro-oncology, Vol. 13, Issue 6, pp. 622-34, (2011) (PubMed).
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- Antigène
- MELK (Maternal Embryonic Leucine Zipper Kinase (MELK))
- Autre désignation
- MELK (MELK Produits)
- Synonymes
- anticorps MELK, anticorps xmelk, anticorps Melk, anticorps HPK38, anticorps AI327312, anticorps MPK38, anticorps mKIAA0175, anticorps fb71b01, anticorps fe01f04, anticorps wu:fb71b01, anticorps wu:fe01f04, anticorps maternal embryonic leucine zipper kinase, anticorps maternal embryonic leucine zipper kinase L homeolog, anticorps MELK, anticorps melk, anticorps cgd5_2270, anticorps Melk, anticorps melk.L
- Sujet
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Description: Maternal embryonic leucine-zipper kinase (MELK) is a key regulator of survival of stemlike GBM cells in vitro. MELK expression is increased in breast cancer tissue and this increase is also associated with poor patient survival, as predicted for a candidate oncogene.
Aliases: HPK38
- Poids moléculaire
- 74.6 kDa
- ID gène
- 9833
- HGNC
- 9833
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