PPP2R4 anticorps

N° du produit ABIN969557

Détail du produit anti-PPP2R4 anticorps

Antigène: PPP2R4 (Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PPP2R4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Purification: purified

Immunogène: Purified recombinant fragment of human PPP2R4 expressed in E. coli.

Clone: 4D9

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Références pour anticorps anti-PPP2R4 (ABIN969557)

Yoon, Jun, Park, Jun Yoo, Moon, Soon Baik, Kim, Kim, Kim, Koh, Taek Lee, You: "Optimal suppression of protein phosphatase 2A activity is critical for maintenance of human embryonic stem cell self-renewal." dans: Stem cells (Dayton, Ohio), Vol. 28, Issue 5, pp. 874-84, (2010) (PubMed).

Singh, Ye, Bucur, Zhu, Tanya Santos, Rabinovitz, Wei, Gao, Hahn, Khosravi-Far: "Protein phosphatase 2A reactivates FOXO3a through a dynamic interplay with 14-3-3 and AKT." dans: Molecular biology of the cell, Vol. 21, Issue 6, pp. 1140-52, (2010) (PubMed).

Détails sur PPP2R4

Antigène: PPP2R4 (Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4))

Autre désignation: PPP2R4 (PPP2R4 Produits)

Synonymes: anticorps PP2A, anticorps PR53, anticorps PTPA, anticorps 2610042B21Rik, anticorps C77440, anticorps N28142, anticorps PTPRA, anticorps Ppp2r4, anticorps fc23d07, anticorps ppp2r4, anticorps wu:fc23d07, anticorps zgc:92766, anticorps pp2a, anticorps ppp2r4.L, anticorps pr53, anticorps ptpa, anticorps protein phosphatase 2 phosphatase activator, anticorps protein phosphatase 2 protein activator, anticorps protein phosphatase 2 phosphatase activator L homeolog, anticorps PTPA, anticorps Ptpa, anticorps ptpa, anticorps ptpa.L

Sujet:

Description: Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.

Aliases: PP2A, PR53, PTPA

Poids moléculaire: 41 kDa

ID gène: 5524

HGNC: 5524

Pathways: Signalisation PI3K-Akt, M Phase, Hepatitis C, Toll-Like Receptors Cascades