APC Produits
(Adenomatous Polyposis Coli (APC))
Catégories
This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Jul 2008].
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Catégories APC en vedette
APC Anticorps
High quality antibodies with extensive validation data.
APC Kits ELISA
Reliable ELISA kits for a wide range of species.
APC Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
APC recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (7)
N° du produit
ABIN7439342
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC
Validations
- (5)
N° du produit
ABIN1678690
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (3)
N° du produit
ABIN7439345
Quantité
100 μL
Fiche technique
Fiche technique
APC recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6953476
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6964614
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6953477
Quantité
96 tests
Fiche technique
Fiche technique
APC recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7121704
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1345292
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7505206
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits APC
: "Microglia permit climbing fiber elimination by promoting GABAergic inhibition in the developing cerebellum." dans: Nature communications, Vol. 9, Issue 1, pp. 2830, (2018) (PubMed).: "Comparison of Selected Protein Levels in Tumour and Surgical Margin in a Group of Patients with Oral Cavity Cancer." dans: Biochemical genetics, Vol. 55, Issue 4, pp. 322-334, (2017) (PubMed).
: "Promoter methylation status of tumor suppressor genes and inhibition of expression of DNA methyltransferase 1 in non-small cell lung cancer." dans: Experimental biology and medicine (Maywood, N.J.), Vol. 241, Issue 14, pp. 1531-9, (2017) (PubMed).
: "Disruption of the RP-MDM2-p53 pathway accelerates APC loss-induced colorectal tumorigenesis." dans: Oncogene, (2016) (PubMed).
: "Genetic reconstitution of tumorigenesis in primary intestinal cells." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 27, pp. 11127-32, (2013) (PubMed).
: "Plasma membrane recruitment of dephosphorylated beta-catenin upon activation of the Wnt pathway." dans: Journal of cell science, Vol. 121, Issue Pt 11, pp. 1793-802, (2008) (PubMed).
: "Cadherins, catenins and APC in pleural malignant mesothelioma." dans: The Journal of pathology, Vol. 201, Issue 3, pp. 355-62, (2003) (PubMed).
Synonymes et noms alternatifs relatifs à APC
APC, WNT signaling pathway regulator (APC), adenomatous polyposis coli (apc), adenomatous polyposis coli protein, putative (Smp_139190), adenomatosis polyposis coli (Apc), APC, WNT signaling pathway regulator (Apc), adenomatous polyposis coli L homeolog (apc.L), AI047805, APC1, AU020952, AW124434, BTPS2, CC1, dp2, DP2, dp2.5, DP2.5, dp3, DP3, fap, fpc, GS, mAPC, Min, PPP1R46, RATAPC, xapcProtein level used designations for APC
- adenomatosis polyposis coli
- adenomatous polyposis coli protein
- multiple intestinal neoplasia
- adenomatosis polyposis coli tumor suppressor
- deleted in polyposis 2.5
- protein phosphatase 1, regulatory subunit 46
- adenomatous polyposis coli homolog
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