APEX1 Produits
(Apurinic/Apyrimidinic Endonuclease 1 (APEX1))
Catégories
Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene\; all encode the same protein. [provided by RefSeq, Jul 2008].
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Catégories APEX1 en vedette
APEX1 Anticorps
High quality antibodies with extensive validation data.
APEX1 Kits ELISA
Reliable ELISA kits for a wide range of species.
APEX1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
APEX1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, FACS
Validations
- (8)
N° du produit
ABIN5611191
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF, IHC (p)
Validations
- (6)
N° du produit
ABIN513392
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Dog, Human, Monkey
Application
WB, IHC, IHC (p)
Validations
- (8)
N° du produit
ABIN1490625
Quantité
100 μL
Fiche technique
Fiche technique
APEX1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6964918
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6974754
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6953823
Quantité
96 tests
Fiche technique
Fiche technique
APEX1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
N° du produit
ABIN1345305
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7121878
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7121879
Quantité
50 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits APEX1
: "Targeting Histone Chaperone FACT Complex Overcomes 5-Fluorouracil Resistance in Colon Cancer." dans: Molecular cancer therapeutics, Vol. 19, Issue 1, pp. 258-269, (2020) (PubMed).: "The long noncoding RNA ROCKI regulates inflammatory gene expression." dans: The EMBO journal, Vol. 38, Issue 8, (2019) (PubMed).
: "Endonuclease and redox activities of human apurinic/apyrimidinic endonuclease 1 have distinctive and essential functions in IgA class switch recombination." dans: The Journal of biological chemistry, Vol. 294, Issue 13, pp. 5198-5207, (2019) (PubMed).
: "The Molecular Chaperone Heat Shock Protein 70 Controls Liver Cancer Initiation and Progression by Regulating Adaptive DNA Damage and Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated ..." dans: Molecular and cellular biology, Vol. 39, Issue 9, (2019) (PubMed).
: "Serum AP-endonuclease 1 (sAPE1) as novel biomarker for hepatocellular carcinoma." dans: Oncotarget, Vol. 10, Issue 3, pp. 383-394, (2019) (PubMed).
: "Inactivation of XPF Sensitizes Cancer Cells to Gemcitabine." dans: Journal of nucleic acids, Vol. 2019, pp. 6357609, (2019) (PubMed).
: "APE1 and NPM1 protect cancer cells from platinum compounds cytotoxicity and their expression pattern has a prognostic value in TNBC." dans: Journal of experimental & clinical cancer research : CR, Vol. 38, Issue 1, pp. 309, (2019) (PubMed).
: "The endonuclease APE1 processes miR-92b formation, thereby regulating expression of the tumor suppressor LDLR in cervical cancer cells." dans: Therapeutic advances in medical oncology, Vol. 11, pp. 1758835919855859, (2019) (PubMed).
: "ATP Binding Cassette Transporter A1 is Involved in Extracellular Secretion of Acetylated APE1/Ref-1." dans: International journal of molecular sciences, Vol. 20, Issue 13, (2019) (PubMed).
: "Decreased APE-1 by Nitroxoline Enhances Therapeutic Effect in a Temozolomide-resistant Glioblastoma: Correlation with Diffusion Weighted Imaging." dans: Scientific reports, Vol. 9, Issue 1, pp. 16613, (2019) (PubMed).
Synonymes et noms alternatifs relatifs à APEX1
apurinic/apyrimidinic endodeoxyribonuclease 1 (APEX1), APEX nuclease (multifunctional DNA repair enzyme) 1 (apex1), APEX nuclease (multifunctional DNA repair enzyme) 1 L homeolog (apex1.L), DNA-(apurinic or apyrimidinic site) lyase (CNG03640), DNA-(apurinic or apyrimidinic site) lyase (CNH01280), DNA-(apurinic or apyrimidinic site) lyase (nth), DNA-(apurinic or apyrimidinic site) lyase (Spirs_4119), DNA-(apurinic or apyrimidinic site) lyase (Palpr_0103), apurinic/apyrimidinic endodeoxyribonuclease 1 (Apex1), apurinic/apyrimidinic endonuclease 1 (Apex1), APE, APE1, APEN, APEX, Apex, apex1, apex1a, APX, BAP1, HAP1, hm:zehn1532, MGC76280, MGC78928, MGC79645, REF-1, Ref-1, REF1, wu:fc13d11, zgc:66204Protein level used designations for APEX1
- DNA-(apurinic or apyrimidinic site) lyase
- APEX nuclease 1
- APEX nuclease (multifunctional DNA repair enzyme) 1
- AP endonuclease class I
- AP lyase
- apurinic-apyrimidinic endonuclease 1
- apurinic/apyrimidinic (abasic) endonuclease
- deoxyribonuclease (apurinic or apyrimidinic)
- protein REF-1
- redox factor-1
- AP endonuclease 1
- APEN
- apurinic/apyrimidinic endonuclease 1
- apurinic/apyrimidinic endonuclease
- zap1
- Apurinic-apyrimidinic endonuclease 1
- Redox factor-1
- APEX nuclease
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