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APOA5 Produits

(Apolipoprotein A-V (APOA5))

Catégories

The protein encoded by this gene is an apolipoprotein that plays an important role in regulating the plasma triglyceride levels, a major risk factor for coronary artery disease. It is a component of high density lipoprotein and is highly similar to a rat protein that is upregulated in response to liver injury. Mutations in this gene have been associated with hypertriglyceridemia and hyperlipoproteinemia type 5. This gene is located proximal to the apolipoprotein gene cluster on chromosome 11q23. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Oct 2009].

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Catégories APOA5 en vedette

APOA5 Anticorps

High quality antibodies with extensive validation data.

APOA5 Kits ELISA

Reliable ELISA kits for a wide range of species.

APOA5 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

APOA5 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (5)
N° du produit ABIN7434506
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (5)
N° du produit ABIN7427942
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (3)
N° du produit ABIN7438598
Quantité 100 μL
Fiche technique Fiche technique

APOA5 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
  • (4)
  • (1)
N° du produit ABIN6973943
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6963557
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6999564
Quantité 96 tests
Fiche technique Fiche technique

APOA5 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
N° du produit ABIN1345336
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7273849
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN5853437
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits APOA5

Lightbourne, Wolska, Abel, Rother, Walter, Kushchayeva, Auh, Shamburek, Remaley, Muniyappa, Brown: "Apolipoprotein CIII and Angiopoietin-like Protein 8 are Elevated in Lipodystrophy and Decrease after Metreleptin." dans: Journal of the Endocrine Society, Vol. 5, Issue 2, pp. bvaa191, (2021) (PubMed).

Zhu, Zhang, Zhou, Li, Li, Fang, Yang, Shan, Li, Chen, Zhou, Ye, Yu, Li, Cai, Liu, Zhang, Wang, Lai, Ruan, Sun, Zhang, Wang, Liu, Xu, Ling, Xu, Zhang, Lv, Yuan, Zhang, Zhang, Shi, Lai: "Susceptibility loci for metabolic syndrome and metabolic components identified in Han Chinese: a multi-stage genome-wide association study." dans: Journal of cellular and molecular medicine, Vol. 21, Issue 6, pp. 1106-1116, (2018) (PubMed).

Zheng, Yu, Xie, Zhao, Wu: "Apolipoprotein A5 regulates intracellular triglyceride metabolism in adipocytes." dans: Molecular medicine reports, Vol. 16, Issue 5, pp. 6771-6779, (2018) (PubMed).

Kim, Kim, Yoo, Lee, Chae, Lee, Lee: "A promoter variant of the APOA5 gene increases atherogenic LDL levels and arterial stiffness in hypertriglyceridemic patients." dans: PLoS ONE, Vol. 12, Issue 12, pp. e0186693, (2018) (PubMed).

Ngaosuwan, Houngngam, Limpisook, Plengpanich, Khovidhunkit: "Apolipoprotein A-V is not a major determinant of triglyceride levels during human sepsis." dans: Journal of critical care, Vol. 30, Issue 4, pp. 727-31, (2015) (PubMed).

van den Berg, Heemskerk, Geerling, van Klinken, Schaap, Bijland, Berbée, van Harmelen, Pronk, Schreurs, Havekes, Rensen, van Dijk: "Apolipoprotein A5 deficiency aggravates high-fat diet-induced obesity due to impaired central regulation of food intake." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 27, Issue 8, pp. 3354-62, (2013) (PubMed).

Guardiola, Alvaro, Vallvé, Rosales, Solà, Girona, Serra, Duran, Esteve, Masana, Ribalta: "APOA5 gene expression in the human intestinal tissue and its response to in vitro exposure to fatty acid and fibrate." dans: Nutrition, metabolism, and cardiovascular diseases : NMCD, Vol. 22, Issue 9, pp. 756-62, (2012) (PubMed).

Hubacek, Wang, Skodová, Adámková, Vráblík, Horínek, Stulc, Ceska, Talmud: "APOA5 Ala315>Val, identified in patients with severe hypertriglyceridemia, is a common mutation with no major effects on plasma lipid levels." dans: Clinical chemistry and laboratory medicine : CCLM / FESCC, Vol. 46, Issue 6, pp. 773-7, (2008) (PubMed).

Dorfmeister, Zeng, Dichlberger, Nilsson, Schaap, Hubacek, Merkel, Cooper, Lookene, Putt, Whittall, Lee, Lins, Delsaux, Nierman, Kuivenhoven, Kastelein, Vrablik, Olivecrona, Schneider, Heeren et al.: "Effects of six APOA5 variants, identified in patients with severe hypertriglyceridemia, on in vitro lipoprotein lipase activity and receptor binding. ..." dans: Arteriosclerosis, thrombosis, and vascular biology, Vol. 28, Issue 10, pp. 1866-71, (2008) (PubMed).

Corella, Lai, Demissie, Cupples, Manning, Tucker, Ordovas: "APOA5 gene variation modulates the effects of dietary fat intake on body mass index and obesity risk in the Framingham Heart Study." dans: Journal of molecular medicine (Berlin, Germany), Vol. 85, Issue 2, pp. 119-28, (2007) (PubMed).

Synonymes et noms alternatifs relatifs à APOA5

apolipoprotein A5 (APOA5), apolipoprotein A-V (Apoa5), apolipoprotein A5 (Apoa5), apolipoprotein A5 L homeolog (apoa5.L), apolipoprotein A5 (apoa5), 1300007O05Rik, apo-AV, apoA-V, apoa-v, APOA5, APOAV, Apoav, apoav, MGC140487, RAP3, rap3

Protein level used designations for APOA5

  • apo-AV
  • apolipoprotein A5
  • regeneration-associated protein 3
  • apoA-V
  • apolipoprotein AV
  • apolipoprotein A-V
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