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APOB Produits

(Apolipoprotein B (APOB))

Catégories

This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq, Jul 2008].

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Catégories APOB en vedette

APOB Anticorps

High quality antibodies with extensive validation data.

APOB Kits ELISA

Reliable ELISA kits for a wide range of species.

APOB Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

APOB recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (10)
N° du produit ABIN7429130
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (5)
N° du produit ABIN7426895
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application ELISA, ICC, FACS
Validations
  • (2)
  • (4)
N° du produit ABIN968961
Quantité 100 μL
Fiche technique Fiche technique

APOB recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (3)
  • (5)
N° du produit ABIN6730915
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (3)
  • (1)
  • (1)
N° du produit ABIN612664
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6963642
Quantité 96 tests
Fiche technique Fiche technique

APOB recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7121865
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7121866
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1345338
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits APOB

Tomassen, Govers, Vos, de Wit: "Dietary fat induced chylomicron-mediated LPS translocation in a bicameral Caco-2cell model." dans: Lipids in health and disease, Vol. 22, Issue 1, pp. 4, (2023) (PubMed).

Matsumoto, Takahashi, Chang, Wu, Yamamoto, Ishihama, Takakura: "Blood concentrations of small extracellular vesicles are determined by a balance between abundant secretion and rapid clearance." dans: Journal of extracellular vesicles, Vol. 9, Issue 1, pp. 1696517, (2020) (PubMed).

Emmer, Lascuna, Tang, Kotnik, Saunders, Khoriaty, Ginsburg: "Murine Surf4 is essential for early embryonic development." dans: PLoS ONE, Vol. 15, Issue 1, pp. e0227450, (2020) (PubMed).

Morishita, Zhao, Tamura, Nishimura, Kanda, Sakamaki, Okazaki, Li, Mizushima: "A critical role of VMP1 in lipoprotein secretion." dans: eLife, Vol. 8, (2020) (PubMed).

Lin, Liddle, Neizer, Robinson, Wright: "Acute whole apple consumption did not influence postprandial lipaemia: a randomised crossover trial." dans: The British journal of nutrition, Vol. 123, Issue 7, pp. 807-817, (2020) (PubMed).

Yu, Rimbert, Palmer, Toyohara, Xia, Xia, Ferreira, Chen, Chen, Loaiza, Horwitz, Kacergis, Zhao, Soukas, Kuivenhoven, Kathiresan, Cowan: "GPR146 Deficiency Protects against Hypercholesterolemia and Atherosclerosis." dans: Cell, Vol. 179, Issue 6, pp. 1276-1288.e14, (2020) (PubMed).

Ganesan, Sinniah, Chik, Alshawsh: "Punicalagin Regulates Apoptosis-Autophagy Switch via Modulation of Annexin A1 in Colorectal Cancer." dans: Nutrients, Vol. 12, Issue 8, (2020) (PubMed).

Carnevale, Pastori, Nocella, Cammisotto, Bartimoccia, Novo, Del Ben, Farcomeni, Angelico, Violi: "Gut-derived lipopolysaccharides increase post-prandial oxidative stress via Nox2 activation in patients with impaired fasting glucose tolerance: effect of extra-virgin olive oil." dans: European journal of nutrition, Vol. 58, Issue 2, pp. 843-851, (2019) (PubMed).

Sołtysik, Ohsaki, Tatematsu, Cheng, Fujimoto: "Nuclear lipid droplets derive from a lipoprotein precursor and regulate phosphatidylcholine synthesis." dans: Nature communications, Vol. 10, Issue 1, pp. 473, (2019) (PubMed).

Lu, Yuan, Wang, Zhang, Yuan, Wu, Zhou, He, Lu, Chen, Fan, Liang, Cheng: "Spontaneous severe hypercholesterolemia and atherosclerosis lesions in rabbits with deficiency of low-density lipoprotein receptor (LDLR) on exon 7." dans: EBioMedicine, Vol. 36, pp. 29-38, (2019) (PubMed).

Synonymes et noms alternatifs relatifs à APOB

apolipoprotein B (APOB), apolipoprotein B (Apob), Ac1-060, AI315052, APOB, ApoB(100), ApoB-48, apob-48, Apo B-100, ApoB-100, apob-100, APOB-100, FLDB, LDLCQ4

Protein level used designations for APOB

  • apo B-100
  • apoB-100
  • apoB-48
  • apolipoprotein B (including Ag(x) antigen)
  • apolipoprotein B-100
  • apolipoprotein B48
  • mutant Apo B 100
  • apolipoprotein B PI
  • apolipoprotein B-48
  • apolipoprotein B
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