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APOBEC3H Produits

(Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3H (APOBEC3H))

Catégories

This gene encodes a member of the apolipoprotein B mRNA-editing enzyme catalytic polypeptide 3 family of proteins. The encoded protein is a cytidine deaminase that has antiretroviral activity by generating lethal hypermutations in viral genomes. Polymorphisms and alternative splicing in this gene influence its antiretroviral activity and are associated with increased resistence to human immunodeficiency virus type 1 infection in certain populations. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009].

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Catégories APOBEC3H en vedette

APOBEC3H Anticorps

High quality antibodies with extensive validation data.

APOBEC3H Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

APOBEC3H recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (3)
N° du produit ABIN531149
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (1)
N° du produit ABIN6259988
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Monkey
Application WB
Validations
N° du produit ABIN6749340
Quantité 100 μL
Fiche technique Fiche technique

APOBEC3H recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1345363
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3087960
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Rhesus Monkey
Source Yeast
Validations
N° du produit ABIN1620112
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits APOBEC3H

Ebrahimi, Richards, Carpenter, Wang, Ikeda, Becker, Cheng, McCann, Shaban, Salamango, Starrett, Lingappa, Yong, Brown, Harris: "Genetic and mechanistic basis for APOBEC3H alternative splicing, retrovirus restriction, and counteraction by HIV-1 protease." dans: Nature communications, Vol. 9, Issue 1, pp. 4137, (2019) (PubMed).

Wang, Becker, Shi, Lauer, Salamango, Aihara, Shaban, Harris: "The Role of RNA in HIV-1 Vif-Mediated Degradation of APOBEC3H." dans: Journal of molecular biology, Vol. 431, Issue 24, pp. 5019-5031, (2019) (PubMed).

Salamango, Becker, McCann, Cheng, Demir, Amaro, Brown, Shaban, Harris: "APOBEC3H Subcellular Localization Determinants Define Zipcode for Targeting HIV-1 for Restriction." dans: Molecular and cellular biology, Vol. 38, Issue 23, (2018) (PubMed).

Starrett, Luengas, McCann, Ebrahimi, Temiz, Love, Feng, Adolph, Chelico, Law, Carpenter, Harris: "The DNA cytosine deaminase APOBEC3H haplotype I likely contributes to breast and lung cancer mutagenesis." dans: Nature communications, Vol. 7, pp. 12918, (2016) (PubMed).

Ooms, Letko, Simon: "The Structural Interface between HIV-1 Vif and Human APOBEC3H." dans: Journal of virology, Vol. 91, Issue 5, (2016) (PubMed).

Refsland, Hultquist, Luengas, Ikeda, Shaban, Law, Brown, Reilly, Emerman, Harris: "Natural polymorphisms in human APOBEC3H and HIV-1 Vif combine in primary T lymphocytes to affect viral G-to-A mutation levels and infectivity." dans: PLoS genetics, Vol. 10, Issue 11, pp. e1004761, (2014) (PubMed).

Shaban, Shi, Lauer, Carpenter, Richards, Salamango, Wang, Lopresti, Banerjee, Levin-Klein, Brown, Aihara, Harris: "The Antiviral and Cancer Genomic DNA Deaminase APOBEC3H Is Regulated by an RNA-Mediated Dimerization Mechanism." dans: Molecular cell, Vol. 69, Issue 1, pp. 75-86.e9 (PubMed).

Synonymes et noms alternatifs relatifs à APOBEC3H

apolipoprotein B mRNA editing enzyme catalytic subunit 3H (APOBEC3H), A3H, APOBEC3A, ARP10

Protein level used designations for APOBEC3H

  • APOBEC-related protein 10
  • ARP-10
  • DNA dC->dU-editing enzyme APOBEC-3H
  • apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3H
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