APOE Produits
(Apolipoprotein E (APOE))
Catégories
Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jul 2008].
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Catégories APOE en vedette
APOE Anticorps
High quality antibodies with extensive validation data.
APOE Kits ELISA
Reliable ELISA kits for a wide range of species.
APOE Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
APOE recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (9)
N° du produit
ABIN7429133
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (9)
N° du produit
ABIN7429139
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Dog
Application
WB, IHC, IP, ICC
Validations
- (7)
N° du produit
ABIN7440422
Quantité
100 μL
Fiche technique
Fiche technique
APOE recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
- (1)
N° du produit
ABIN612665
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Competition ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6975758
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Competition ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6974557
Quantité
96 tests
Fiche technique
Fiche technique
APOE recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
N° du produit
ABIN7273868
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (2)
N° du produit
ABIN7273871
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (2)
N° du produit
ABIN7273869
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits APOE
: "Isoform- and cell-state-specific lipidation of ApoE in astrocytes." dans: Cell reports, Vol. 38, Issue 9, pp. 110435, (2022) (PubMed).: "Hepatic HuR modulates lipid homeostasis in response to high-fat diet." dans: Nature communications, Vol. 11, Issue 1, pp. 3067, (2020) (PubMed).
: "Apolipoprotein E is a concentration-dependent pulmonary danger signal that activates the NLRP3 inflammasome and IL-1β secretion by bronchoalveolar fluid macrophages from asthmatic subjects." dans: The Journal of allergy and clinical immunology, Vol. 144, Issue 2, pp. 426-441.e3, (2020) (PubMed).
: "Generation of a set of isogenic, gene-edited iPSC lines homozygous for all main APOE variants and an APOE knock-out line." dans: Stem cell research, Vol. 34, pp. 101349, (2019) (PubMed).
: "APOE ε2 is associated with increased tau pathology in primary tauopathy. ..." dans: Nature communications, Vol. 9, Issue 1, pp. 4388, (2019) (PubMed).
: "Spontaneous severe hypercholesterolemia and atherosclerosis lesions in rabbits with deficiency of low-density lipoprotein receptor (LDLR) on exon 7." dans: EBioMedicine, Vol. 36, pp. 29-38, (2019) (PubMed).
: "Single-Cell RNA Sequencing Identifies Candidate Renal Resident Macrophage Gene Expression Signatures across Species." dans: Journal of the American Society of Nephrology : JASN, Vol. 30, Issue 5, pp. 767-781, (2019) (PubMed).
: "Acute Loss of Apolipoprotein E Triggers an Autoimmune Response That Accelerates Atherosclerosis." dans: Arteriosclerosis, thrombosis, and vascular biology, Vol. 38, Issue 8, pp. e145-e158, (2019) (PubMed).
: "Evaluation of α-synuclein and apolipoprotein E as potential biomarkers in cerebrospinal fluid to monitor pharmacotherapeutic efficacy in dopamine dictated disease states of Parkinson's disease and ..." dans: Neuropsychiatric disease and treatment, Vol. 15, pp. 2073-2085, (2019) (PubMed).
: "Hypolipidemic and anti-inflammatory effects of aorta and heart tissues of cattle and pigs in the atherosclerosis rat model." dans: Animal science journal = Nihon chikusan Gakkaihō, Vol. 89, Issue 5, pp. 784-793, (2018) (PubMed).
Synonymes et noms alternatifs relatifs à APOE
apolipoprotein E (apoe), apolipoprotein Ea (apoea), apolipoprotein E (Apoe), apolipoprotein E (APOE), ad2, AD2, AI255918, Apo-E, apoe, APOEA, apoprotein, im:7036787, LDLCQ5, LPG, wu:fb69a05, zgc:110064Protein level used designations for APOE
- apolipoprotein E
- ApoE-1
- apo-E
- apolipoprotein E3
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