APP Produits
(Amyloid beta (A4) Precursor Protein (APP))
Catégories
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.
Catégories APP en vedette
APP Anticorps
High quality antibodies with extensive validation data.
APP Kits ELISA
Reliable ELISA kits for a wide range of species.
APP Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
APP recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IF, IHC (p), ICC, IHC (fro)
Validations
- (7)
- (1)
N° du produit
ABIN2855011
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC
Validations
- (4)
- (1)
N° du produit
ABIN3020680
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IF
Validations
- (2)
- (1)
N° du produit
ABIN197432
Quantité
0.1 mL
Fiche technique
Fiche technique
APP recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
N° du produit
ABIN6953681
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6999550
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6953682
Quantité
96 tests
Fiche technique
Fiche technique
APP recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1345399
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1345401
Quantité
25 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
N° du produit
ABIN7092740
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits APP
: "Involvement of Insulin Signaling Disturbances in Bisphenol A-Induced Alzheimer's Disease-like Neurotoxicity." dans: Scientific reports, Vol. 7, Issue 1, pp. 7497, (2019) (PubMed).: "Polarization of Microglia to the M2 Phenotype in a Peroxisome Proliferator-Activated Receptor Gamma-Dependent Manner Attenuates Axonal Injury Induced by Traumatic Brain Injury in Mice." dans: Journal of neurotrauma, (2018) (PubMed).
: "β-Sheet Breaker Peptide-HPYD for the Treatment of Alzheimer's Disease: Primary Studies on Behavioral Test and Transcriptional Profiling." dans: Frontiers in pharmacology, Vol. 8, pp. 969, (2018) (PubMed).
: "Adapentpronitrile, a New Dipeptidyl Peptidase-IV Inhibitor, Ameliorates Diabetic Neuronal Injury Through Inhibiting Mitochondria-Related Oxidative Stress and Apoptosis." dans: Frontiers in cellular neuroscience, Vol. 12, pp. 214, (2018) (PubMed).
: "Vitamin D receptor is present on the neuronal plasma membrane and is co-localized with amyloid precursor protein, ADAM10 or Nicastrin." dans: PLoS ONE, Vol. 12, Issue 11, pp. e0188605, (2017) (PubMed).
: "Effect of general anesthesia on serum β-amyloid protein and regional cerebral oxygen saturation of elderly patients after subtotal gastrectomy." dans: Experimental and therapeutic medicine, Vol. 12, Issue 6, pp. 3561-3566, (2017) (PubMed).
: "Molecular Anatomy of Palate Development." dans: PLoS ONE, Vol. 10, Issue 7, pp. e0132662, (2015) (PubMed).
: "Studying the relationship between cell cycle and Alzheimer's disease by gold nanoparticle probes." dans: Analytical biochemistry, Vol. 489, pp. 32-7, (2015) (PubMed).
: "Specific amyloid β clearance by a catalytic antibody construct." dans: The Journal of biological chemistry, Vol. 290, Issue 16, pp. 10229-41, (2015) (PubMed).
: "Anti-autophagic and anti-apoptotic effects of memantine in a SH-SY5Y cell model of Alzheimer's disease via mammalian target of rapamycin-dependent and -independent pathways." dans: Molecular medicine reports, Vol. 12, Issue 5, pp. 7615-22, (2015) (PubMed).
Synonymes et noms alternatifs relatifs à APP
amyloid beta precursor protein (APP), amyloid beta (A4) precursor protein (APP), amyloid beta precursor protein (app), beta amyloid protein precursor-like (Appl), amyloid beta precursor protein (App), amyloid beta (A4) precursor protein (App), amyloid beta (A4) precursor protein a (appa), amyloid beta precursor protein L homeolog (app.L), AAA, aaa, ABETA, abeta, Abeta, ABPP, abpp, Abpp, AD1, ad1, Adap, Ag, APP, app, APP-like, APPI, appi, APPL, appl, BcDNA:GH04413, betaApp, CG7727, CTFgamma, ctfgamma, CVAP, cvap, Cvap, Dmel\\CG7727, E030013M08Rik, EG:65F1.5, PN-II, PN2, pn2, wu:fj34d10, wu:fk65e12, zgc:85740Protein level used designations for APP
- alzheimer disease amyloid protein
- amyloid beta A4 protein
- beta-amyloid peptide
- cerebral vascular amyloid peptide
- peptidase nexin-II
- preA4
- protease nexin-II
- amyloid protein
- ABPP
- alzheimer disease amyloid A4 protein homolog
- amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease)
- Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimers disease amyloid protein) (Cerebral vascular amyloid peptide) (CVAP) (Protease nexin-II) (PN-II) (APPI) (PreA4)
- amyloid beta (A4) precursor protein (peptidase nexin-2, Alzheimer disease)
- amyloid beta (A4) precursor protein (protease nexin-II, Alzheimer disease)
- beta-amyloid precursor protein
- Appl-PA
- Appl-PB
- Appl-PC
- Appl-PD
- Appl-PE
- Appl-PF
- CG7727-PA
- CG7727-PB
- CG7727-PC
- CG7727-PD
- CG7727-PE
- CG7727-PF
- amyloid precursor protein
- amyloid precursor protein-like
- beta-amyloid-protein-precursor-like
- AG
- amyloid A4
- amyloidogenic glycoprotein
- appican
- protease nexin II
- amyloid beta precursor protein a
- beta-amyloid precursor protein A
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