APPL1 Produits
(Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 1 (APPL1))
Catégories
The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008].
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Catégories APPL1 en vedette
APPL1 Anticorps
High quality antibodies with extensive validation data.
APPL1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
APPL1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse
Application
WB, ELISA, IHC
Validations
- (3)
N° du produit
ABIN7234818
Quantité
200 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
N° du produit
ABIN565220
Quantité
50 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
N° du produit
ABIN7149501
Quantité
100 μg
Fiche technique
Fiche technique
APPL1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6205982
Quantité
96 tests
Fiche technique
Fiche technique
APPL1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7121695
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1345406
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1345408
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits APPL1
: "APPL1 promotes glucose uptake in response to mechanical stretch via the PKCζ-non-muscle myosin IIa pathway in C2C12 myotubes." dans: Cellular signalling, Vol. 28, Issue 11, pp. 1694-702, (2016) (PubMed).: "Fiber type-specific differences in glucose uptake by single fibers from skeletal muscles of 9- and 25-month-old rats." dans: The journals of gerontology. Series A, Biological sciences and medical sciences, Vol. 67, Issue 12, pp. 1286-94, (2012) (PubMed).
: "A novel method to measure glucose uptake and myosin heavy chain isoform expression of single fibers from rat skeletal muscle." dans: Diabetes, Vol. 61, Issue 5, pp. 995-1003, (2012) (PubMed).
: "Effects of polysaccharides from Morchella conica on nitric oxide production in lipopolysaccharide-treated macrophages." dans: Applied microbiology and biotechnology, Vol. 94, Issue 3, pp. 763-71, (2012) (PubMed).
: "Mechanisms for increased insulin-stimulated Akt phosphorylation and glucose uptake in fast- and slow-twitch skeletal muscles of calorie-restricted rats." dans: American journal of physiology. Endocrinology and metabolism, Vol. 300, Issue 6, pp. E966-78, (2011) (PubMed).
: "Insulin resistance for glucose uptake and Akt2 phosphorylation in the soleus, but not epitrochlearis, muscles of old vs. adult rats." dans: Journal of applied physiology (Bethesda, Md. : 1985), Vol. 108, Issue 6, pp. 1631-40, (2010) (PubMed).
: "APPL1 binds to adiponectin receptors and mediates adiponectin signalling and function." dans: Nature cell biology, Vol. 8, Issue 5, pp. 516-23, (2006) (PubMed).
: "Identification of a chromosome 3p14.3-21.1 gene, APPL, encoding an adaptor molecule that interacts with the oncoprotein-serine/threonine kinase AKT2." dans: Oncogene, Vol. 18, Issue 35, pp. 4891-8, (1999) (PubMed).
Synonymes et noms alternatifs relatifs à APPL1
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 (APPL1), adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 (Appl1), adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 (Appl1), 2900057D21Rik, 7330406P05Rik, AI585782, APPL, AW209077, BB022931, C88264, DIP13, DIP13alpha, RGD1309388Protein level used designations for APPL1
- AKT2 interactor
- DCC-interacting protein 13-alpha
- adapter protein containing PH domain, PTB domain and leucine zipper motif 1
- adaptor protein containing pH domain, PTB domain and leucine zipper motif 1
- dip13-alpha
- signaling adaptor protein DIP13alpha
- DIP13 alpha
- adaptor protein APPL like
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