ARFGEF2 Anticorps
(ADP-Ribosylation Factor Guanine Nucleotide-Exchange Factor 2 (Brefeldin A-Inhibited) (ARFGEF2))
ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine-nucleotide exchange activity and also brefeldin A inhibition. [provided by RefSeq, Jul 2008].
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Catégories ARFGEF2 en vedette
ARFGEF2 Anticorps
High quality antibodies with extensive validation data.
ARFGEF2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
N° du produit
ABIN7145776
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF, ICC
Validations
- (2)
N° du produit
ABIN6258592
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (1)
N° du produit
ABIN7184628
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits ARFGEF2
: "Arf guanine nucleotide-exchange factors BIG1 and BIG2 regulate nonmuscle myosin IIA activity by anchoring myosin phosphatase complex." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 34, pp. E3162-70, (2013) (PubMed).: "The small G protein Arl1 directs the trans-Golgi-specific targeting of the Arf1 exchange factors BIG1 and BIG2." dans: The Journal of cell biology, Vol. 196, Issue 3, pp. 327-35, (2012) (PubMed).
: "cAMP-dependent protein kinase A (PKA) signaling induces TNFR1 exosome-like vesicle release via anchoring of PKA regulatory subunit RIIbeta to BIG2." dans: The Journal of biological chemistry, Vol. 283, Issue 37, pp. 25364-71, (2008) (PubMed).
Synonymes et noms alternatifs relatifs à ARFGEF2
ADP ribosylation factor guanine nucleotide exchange factor 2 (ARFGEF2), ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) (Arfgef2), ADP ribosylation factor guanine nucleotide exchange factor 2 (Arfgef2), AI463430, AW493672, BIG2, Big2, dJ1164I10.1, E230011G24Rik, PVNH2Protein level used designations for ARFGEF2
- ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
- cytohesin 1-like
- brefeldin A-inhibited GEP 2
- brefeldin A-inhibited guanine nucleotide-exchange protein 2
- Brefeldin A-inhibited guanine nucleotide-exchange factor 2
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