ARHGEF3 Produits
(rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3))
Catégories
Rho-like GTPases are involved in a variety of cellular processes, and they are activated by binding GTP and inactivated by conversion of GTP to GDP by their intrinsic GTPase activity. Guanine nucleotide exchange factors (GEFs) accelerate the GTPase activity of Rho GTPases by catalyzing their release of bound GDP. This gene encodes a guanine nucleotide exchange factor, which specifically activates two members of the Rho GTPase family: RHOA and RHOB, both of which have a role in bone cell biology. It has been identified that genetic variation in this gene plays a role in the determination of bone mineral density (BMD), indicating the implication of this gene in postmenopausal osteoporosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Catégories ARHGEF3 en vedette
ARHGEF3 Anticorps
High quality antibodies with extensive validation data.
ARHGEF3 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
ARHGEF3 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC (p)
Validations
- (1)
- (2)
N° du produit
ABIN652003
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (2)
N° du produit
ABIN7167981
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA
Validations
- (1)
- (1)
N° du produit
ABIN565494
Quantité
50 μL
Fiche technique
Fiche technique
ARHGEF3 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1345551
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1345553
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3089362
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits ARHGEF3
: "The putative tumor activator ARHGEF3 promotes nasopharyngeal carcinoma cell pathogenesis by inhibiting cellular apoptosis." dans: Oncotarget, Vol. 7, Issue 18, pp. 25836-48, (2017) (PubMed).: "ARHGEF3 controls HDACi-induced differentiation via RhoA-dependent pathways in acute myeloid leukemias." dans: Epigenetics : official journal of the DNA Methylation Society, Vol. 10, Issue 1, pp. 6-18, (2015) (PubMed).
: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." dans: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).
Synonymes et noms alternatifs relatifs à ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3, gene 1 S homeolog (arhgef3.1.S), Rho guanine nucleotide exchange factor 3 (ARHGEF3), Rho guanine nucleotide exchange factor (GEF) 3 (arhgef3), Rho guanine nucleotide exchange factor (GEF) 3, gene 1 (arhgef3.1), Rho guanine nucleotide exchange factor (GEF) 3 (ARHGEF3), Rho guanine nucleotide exchange factor (GEF) 3 (Arhgef3), Rho guanine nucleotide exchange factor 3 (Arhgef3), 1200004I24Rik, 9830169H03Rik, ARHGEF3, C76747, DKFZp459N027, GEF3, MGC82822, MGC108040, si:ch211-258l4.8, STA3, XPLN, XplnProtein level used designations for ARHGEF3
- Rho guanine nucleotide exchange factor (GEF) 3
- Rho guanine nucleotide exchange factor 3
- rho guanine nucleotide exchange factor 3
- rho guanine nucleotide exchange factor 3-like
- 59.8 kDA protein
- RhoGEF protein
- exchange factor found in platelets and leukemic and neuronal tissues, XPLN
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