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ARHGEF3 Produits

(rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3))

Catégories

Rho-like GTPases are involved in a variety of cellular processes, and they are activated by binding GTP and inactivated by conversion of GTP to GDP by their intrinsic GTPase activity. Guanine nucleotide exchange factors (GEFs) accelerate the GTPase activity of Rho GTPases by catalyzing their release of bound GDP. This gene encodes a guanine nucleotide exchange factor, which specifically activates two members of the Rho GTPase family: RHOA and RHOB, both of which have a role in bone cell biology. It has been identified that genetic variation in this gene plays a role in the determination of bone mineral density (BMD), indicating the implication of this gene in postmenopausal osteoporosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Catégories ARHGEF3 en vedette

ARHGEF3 Anticorps

High quality antibodies with extensive validation data.

ARHGEF3 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

ARHGEF3 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (1)
  • (2)
N° du produit ABIN652003
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (2)
N° du produit ABIN7167981
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN565494
Quantité 50 μL
Fiche technique Fiche technique

ARHGEF3 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1345551
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1345553
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3089362
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits ARHGEF3

Liu, Zheng, Cai, Guo, Lin, Chen, Liao, Kung, Zeng, Xie: "The putative tumor activator ARHGEF3 promotes nasopharyngeal carcinoma cell pathogenesis by inhibiting cellular apoptosis." dans: Oncotarget, Vol. 7, Issue 18, pp. 25836-48, (2017) (PubMed).

DAmato, DellAversana, Conte, Ciotta, Scisciola, Carissimo, Nebbioso, Altucci: "ARHGEF3 controls HDACi-induced differentiation via RhoA-dependent pathways in acute myeloid leukemias." dans: Epigenetics : official journal of the DNA Methylation Society, Vol. 10, Issue 1, pp. 6-18, (2015) (PubMed).

Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." dans: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).

Synonymes et noms alternatifs relatifs à ARHGEF3

Rho guanine nucleotide exchange factor (GEF) 3, gene 1 S homeolog (arhgef3.1.S), Rho guanine nucleotide exchange factor 3 (ARHGEF3), Rho guanine nucleotide exchange factor (GEF) 3 (arhgef3), Rho guanine nucleotide exchange factor (GEF) 3, gene 1 (arhgef3.1), Rho guanine nucleotide exchange factor (GEF) 3 (ARHGEF3), Rho guanine nucleotide exchange factor (GEF) 3 (Arhgef3), Rho guanine nucleotide exchange factor 3 (Arhgef3), 1200004I24Rik, 9830169H03Rik, ARHGEF3, C76747, DKFZp459N027, GEF3, MGC82822, MGC108040, si:ch211-258l4.8, STA3, XPLN, Xpln

Protein level used designations for ARHGEF3

  • Rho guanine nucleotide exchange factor (GEF) 3
  • Rho guanine nucleotide exchange factor 3
  • rho guanine nucleotide exchange factor 3
  • rho guanine nucleotide exchange factor 3-like
  • 59.8 kDA protein
  • RhoGEF protein
  • exchange factor found in platelets and leukemic and neuronal tissues, XPLN
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