ARNT Produits
(Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))
Catégories
The aryl hydrocarbon (Ah) receptor is involved in the induction of several enzymes that participate in xenobiotic metabolism. The ligand-free, cytosolic form of the Ah receptor is complexed to heat shock protein 90. Binding of ligand, which includes dioxin and polycyclic aromatic hydrocarbons, results in translocation of the ligand-binding subunit only to the nucleus. Induction of enzymes involved in xenobiotic metabolism occurs through binding of the ligand-bound Ah receptor to xenobiotic responsive elements in the promoters of genes for these enzymes. This gene encodes a protein that forms a complex with the ligand-bound Ah receptor, and is required for receptor function. The encoded protein has also been identified as the beta subunit of a heterodimeric transcription factor, hypoxia-inducible factor 1. A t(1\;12)(q21\;p13) translocation, which results in a TEL-ARNT fusion protein, is associated with acute myeloblastic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2010].
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Catégories ARNT en vedette
ARNT Anticorps
High quality antibodies with extensive validation data.
ARNT Kits ELISA
Reliable ELISA kits for a wide range of species.
ARNT Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
ARNT recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF, IHC (p), RNAi
Validations
- (7)
N° du produit
ABIN559953
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF
Validations
- (1)
- (4)
N° du produit
ABIN513506
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IF, ICC
Validations
- (4)
N° du produit
ABIN6260045
Quantité
100 μL
Fiche technique
Fiche technique
ARNT recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6953934
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6965029
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6953933
Quantité
96 tests
Fiche technique
Fiche technique
ARNT recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
N° du produit
ABIN1345671
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1345673
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7397531
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits ARNT
: "Molecular cloning and characterization of two ARNT (ARNT-1 and ARNT-2) genes in Atlantic croaker and their expression during coexposure to hypoxia and PCB77." dans: Environmental toxicology, Vol. 34, Issue 2, pp. 160-171, (2019) (PubMed).: "Inherent DNA-binding specificities of the HIF-1α and HIF-2α transcription factors in chromatin." dans: EMBO reports, Vol. 20, Issue 1, (2019) (PubMed).
: "MITF controls the TCA cycle to modulate the melanoma hypoxia response." dans: Pigment cell & melanoma research, (2019) (PubMed).
: "Chemotherapy induces enrichment of CD47+/CD73+/PDL1+ immune evasive triple-negative breast cancer cells." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 6, pp. E1239-E1248, (2018) (PubMed).
: "AhR and SHP regulate phosphatidylcholine and S-adenosylmethionine levels in the one-carbon cycle." dans: Nature communications, Vol. 9, Issue 1, pp. 540, (2018) (PubMed).
: "NF-κB-Dependent Lymphoid Enhancer Co-option Promotes Renal Carcinoma Metastasis." dans: Cancer discovery, Vol. 8, Issue 7, pp. 850-865, (2018) (PubMed).
: "Anti-inflammatory Effects of Phyllanthus emblica L on Benzopyrene-Induced Precancerous Lung Lesion by Regulating the IL-1β/miR-101/Lin28B Signaling Pathway." dans: Integrative cancer therapies, Vol. 16, Issue 4, pp. 505-515, (2018) (PubMed).
: "Metastasis-Associated Protein 1 Deficiency Results in Compromised Pulmonary Alveolar Capillary Angiogenesis in Mice." dans: Medical science monitor : international medical journal of experimental and clinical research, Vol. 23, pp. 3932-3941, (2018) (PubMed).
: "TLR4 promotes the expression of HIF-1α by triggering reactive oxygen species in cervical cancer cells in vitro-implications for therapeutic intervention." dans: Molecular medicine reports, Vol. 17, Issue 2, pp. 2229-2238, (2018) (PubMed).
: "Mutations in an Innate Immunity Pathway Are Associated with Poor Overall Survival Outcomes and Hypoxic Signaling in Cancer." dans: Cell reports, Vol. 25, Issue 13, pp. 3721-3732.e6, (2018) (PubMed).
Synonymes et noms alternatifs relatifs à ARNT
aryl hydrocarbon receptor nuclear translocator (ARNT), aryl hydrocarbon receptor nuclear translocator (Arnt), aryl hydrocarbon receptor nuclear translocator (arnt), aryl hydrocarbon receptor nuclear translocator S homeolog (arnt.S), ARNT, arnt.2, Arnt1, arnt1, bHLHe2, D3Ertd557e, Drnt, ESTM42, HIF-1-beta, HIF-1beta, hif-1beta, HIF1-beta, HIF1B, Hif1b, hif1b, HIF1BETA, hif1beta, MGC68805, mKIAA4051, TANGO, tango, W08714, xArnt, zgc:136664Protein level used designations for ARNT
- class E basic helix-loop-helix protein 2
- dioxin receptor, nuclear translocator
- hypoxia-inducible factor 1, beta subunit
- ARNT protein
- HIF-1 beta
- HIF-1-beta
- HIF1-beta
- aryl hydrocarbon receptor nuclear translocator
- hypoxia-inducible factor 1 beta
- hypoxia-inducible factor 1-beta
- Aryl hydrocarbon receptor nuclear translocator 1
- ARNT1
- aryl hydrocarbon receptor nuclear translocater
- aryl hydrocarbon receptor nuclear translocator 2
- rtARNT
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