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ASIC1 Produits

(Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2))

Catégories

This gene encodes a member of the acid-sensing ion channel (ASIC) family of proteins, which are part of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. Members of the ASIC family are sensitive to amiloride and function in neurotransmission. The encoded proteins function in learning, pain transduction, touch sensation, and development of memory and fear. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2012].

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Catégories ASIC1 en vedette

ASIC1 Anticorps

High quality antibodies with extensive validation data.

ASIC1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

ASIC1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB
Validations
  • (5)
N° du produit ABIN2776229
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (3)
N° du produit ABIN653218
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Rat
Application WB, IHC
Validations
  • (2)
  • (2)
N° du produit ABIN350049
Quantité 500 μg
Fiche technique Fiche technique

ASIC1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6212694
Quantité 96 tests
Fiche technique Fiche technique

ASIC1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1305626
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1305628
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
N° du produit ABIN3135720
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits ASIC1

Sudarikova, Bychkov, Kulbatskii, Chubinskiy-Nadezhdin, Shlepova, Shulepko, Koshelev, Kirpichnikov, Lyukmanova: "Mambalgin-2 Inhibits Lung Adenocarcinoma Growth and Migration by Selective Interaction With ASIC1/α-ENaC/γ-ENaC Heterotrimer." dans: Frontiers in oncology, Vol. 12, pp. 904742, (2022) (PubMed).

Bychkov, Kirichenko, Shulepko, Mikhaylova, Kirpichnikov, Lyukmanova: "Mambalgin-2 Inhibits Growth, Migration, and Invasion of Metastatic Melanoma Cells by Targeting the Channels Containing an ASIC1a Subunit Whose Up-Regulation Correlates with Poor Survival Prognosis." dans: Biomedicines, Vol. 9, Issue 10, (2021) (PubMed).

Lin, Sun, Chen: "Genetic exploration of the role of acid-sensing ion channels." dans: Neuropharmacology, Vol. 94, pp. 99-118, (2015) (PubMed).

Vig, Hearst, Shao, Lopez: "Knockdown of acid-sensing ion channel 1a (ASIC1a) suppresses disease phenotype in SCA1 mouse model." dans: Cerebellum (London, England), Vol. 13, Issue 4, pp. 479-90, (2014) (PubMed).

Chintala, Liu, Parmar, Kamalska, Kim, Lovett, Grant, Chaqour: "Connective tissue growth factor regulates retinal neovascularization through p53 protein-dependent transactivation of the matrix metalloproteinase (MMP)-2 gene." dans: The Journal of biological chemistry, Vol. 287, Issue 48, pp. 40570-85, (2012) (PubMed).

Diochot, Baron, Salinas, Douguet, Scarzello, Dabert-Gay, Debayle, Friend, Alloui, Lazdunski, Lingueglia: "Black mamba venom peptides target acid-sensing ion channels to abolish pain." dans: Nature, Vol. 490, Issue 7421, pp. 552-5, (2012) (PubMed).

Hoagland, Sherwood, Lee, Walker, Askwith: "Identification of a calcium permeable human acid-sensing ion channel 1 transcript variant." dans: The Journal of biological chemistry, Vol. 285, Issue 53, pp. 41852-62, (2010) (PubMed).

Synonymes et noms alternatifs relatifs à ASIC1

acid sensing ion channel subunit 1 (ASIC1), acid sensing ion channel subunit 1 (Asic1), acid sensing ion channel subunit 1 (asic1), acid-sensing (proton-gated) ion channel 1 (Asic1), SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 (SMARCD1), ACCN2, Accn2, AI843610, ASIC, ASIC1, ASIC1a, B530003N02Rik, BNaC2

Protein level used designations for ASIC1

  • Cation channel, amiloride-sensitive, neuronal, 2
  • acid-sensing ion channel 1
  • acid-sensing ion channel 1a protein
  • amiloride-sensitive cation channel 2, neuronal
  • brain sodium channel 2
  • BNaC2
  • proton gated cation channel ASIC1
  • Amiloride-sensitive cation channel 2, neuronal
  • acid sensing ion channel
  • degenerin 2
  • SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1
  • acid-sensing (proton-gated) ion channel 1
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