ASK1 Produits
(Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5))
Catégories
Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells\; MAPKKK5 does not activate MAPK/ERK. [provided by RefSeq, Jul 2008].
antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.
Catégories ASK1 en vedette
ASK1 Anticorps
High quality antibodies with extensive validation data.
ASK1 Kits ELISA
Reliable ELISA kits for a wide range of species.
ASK1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
ASK1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Cow, Human, Mouse, Rat
Application
WB, ELISA, IHC (p), FACS
Validations
- (2)
- (5)
N° du produit
ABIN683128
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
IHC, ELISA, ICC, FACS
Validations
- (1)
- (5)
N° du produit
ABIN969273
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (5)
N° du produit
ABIN517859
Quantité
100 μg
Fiche technique
Fiche technique
ASK1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (3)
- (1)
N° du produit
ABIN6957867
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6968654
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6968655
Quantité
96 tests
Fiche technique
Fiche technique
ASK1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7124004
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1310221
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect Cells
Validations
N° du produit
ABIN5508821
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits ASK1
: "Perilipin 5 Protects against Cellular Oxidative Stress by Enhancing Mitochondrial Function in HepG2 Cells." dans: Cells, Vol. 8, Issue 10, (2020) (PubMed).: "Endoplasmic Reticulum Stress Is Involved in Stress-Induced Hypothalamic Neuronal Injury in Rats via the PERK-ATF4-CHOP and IRE1-ASK1-JNK Pathways." dans: Frontiers in cellular neuroscience, Vol. 13, pp. 190, (2019) (PubMed).
: "Inhibition of apoptosis signal-regulating kinase by paeoniflorin attenuates neuroinflammation and ameliorates neuropathic pain." dans: Journal of neuroinflammation, Vol. 16, Issue 1, pp. 83, (2019) (PubMed).
: "Dual function of peroxiredoxin I in lipopolysaccharide-induced osteoblast apoptosis via reactive oxygen species and the apoptosis signal-regulating kinase 1 signaling pathway." dans: Cell death discovery, Vol. 4, pp. 47, (2018) (PubMed).
: "Differential expression of survival proteins during decreased intracellular oxygen tension in brain endothelial cells of grey mullets." dans: Marine pollution bulletin, Vol. 115, Issue 1-2, pp. 421-428, (2017) (PubMed).
: "Differential regulation of pro- and antiapoptotic proteins in fish adipocytes during hypoxic conditions." dans: Fish physiology and biochemistry, Vol. 42, Issue 3, pp. 919-34, (2016) (PubMed).
: "Peroxiredoxin 1 Promotes Pancreatic Cancer Cell Invasion by Modulating p38 MAPK Activity." dans: Pancreas, Vol. 44, Issue 2, pp. 331-40, (2015) (PubMed).
: "Calcium/Ask1/MKK7/JNK2/c-Src signalling cascade mediates disruption of intestinal epithelial tight junctions by dextran sulfate sodium." dans: The Biochemical journal, Vol. 465, Issue 3, pp. 503-15, (2015) (PubMed).
: "Ginsenoside Rd inhibits apoptosis following spinal cord ischemia/reperfusion injury." dans: Neural regeneration research, Vol. 9, Issue 18, pp. 1678-87, (2014) (PubMed).
: "Heat-shock protein 70 modulates apoptosis signal-regulating kinase 1 in stressed hepatocytes of Mugil cephalus." dans: Fish physiology and biochemistry, Vol. 40, Issue 5, pp. 1573-85, (2014) (PubMed).
Synonymes et noms alternatifs relatifs à ASK1
mitogen-activated protein kinase kinase kinase 5 (MAP3K5), mitogen-activated protein kinase kinase kinase 5 (MAPKKK5), mitogen-activated protein kinase kinase kinase 5 (Map3k5), mitogen-activated protein kinase kinase kinase 5 (map3k5), 7420452D20Rik, ASK, ASK1, Ask1, MAPKKK5, MEKK5, Mekk5, mitogen-activated protein kinase kinase kinase 5, MUD21.11, MUD21_11, RGD1306565Protein level used designations for ASK1
- ASK-1
- MAP/ERK kinase kinase 5
- MAPK/ERK kinase kinase 5
- MEK kinase 5
- MEKK 5
- apoptosis signal regulating kinase 1
- apoptosis signal-regulating kinase 1
- mitogen activated protein kinase kinase kinase 5
- mitogen-activated protein kinase kinase kinase 5
- mitogen-activated protein kinase kinase kinase 5 pseudogene
Vous êtes ici:
