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ATF4 Produits

(Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4))

Catégories

This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication. [provided by RefSeq, Sep 2011].

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Catégories ATF4 en vedette

ATF4 Anticorps

High quality antibodies with extensive validation data.

ATF4 Kits ELISA

Reliable ELISA kits for a wide range of species.

ATF4 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

ATF4 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, ICC, IP
Validations
  • (7)
N° du produit ABIN7433582
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC, ICC, FACS
Validations
  • (6)
N° du produit ABIN5542583
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IF
Validations
  • (5)
  • (5)
N° du produit ABIN559979
Quantité 100 μg
Fiche technique Fiche technique

ATF4 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6964571
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6964570
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6962050
Quantité 96 tests
Fiche technique Fiche technique

ATF4 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
N° du produit ABIN1345933
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7121669
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7121668
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits ATF4

Lee, Yeh, Lee, Shih, Chen, Hung, You, Wu, Shentu, Huang, Lin, Wu, Lin, Lu, Tsao, Lin, Lo, Tseng, Wu, Chen, Wu, Lin, Sperling, Guzy, Fang, Yang: "Fibroblast-enriched endoplasmic reticulum protein TXNDC5 promotes pulmonary fibrosis by augmenting TGFβ signaling through TGFBR1 stabilization." dans: Nature communications, Vol. 11, Issue 1, pp. 4254, (2020) (PubMed).

Besio, Garibaldi, Leoni, Cipolla, Sabbioneda, Biggiogera, Mottes, Aglan, Otaify, Temtamy, Rossi, Forlino: "Cellular stress due to impairment of collagen prolyl hydroxylation complex is rescued by the chaperone 4-phenylbutyrate." dans: Disease models & mechanisms, Vol. 12, Issue 6, (2019) (PubMed).

Liu, Shen, Wang, Liu, Zheng, Luo: "EndophilinA2 protects against angiotensin II-induced cardiac hypertrophy by inhibiting angiotensin II type 1 receptor trafficking in neonatal rat cardiomyocytes." dans: Journal of cellular biochemistry, (2018) (PubMed).

Zhang, Zhong, Sun, Sun, Zhou: "Adipose-specific lipin1 overexpression in mice protects against alcohol-induced liver injury." dans: Scientific reports, Vol. 8, Issue 1, pp. 408, (2018) (PubMed).

Li, Chen, Yang, Wang, Lin, Xu: "Selenoprotein S silencing triggers mouse hepatoma cells apoptosis and necrosis involving in intracellular calcium imbalance and ROS-mPTP-ATP." dans: Biochimica et biophysica acta. General subjects, Vol. 1862, Issue 10, pp. 2113-2123, (2018) (PubMed).

Anasa, Manickam, Talwar, Ravanan: "Identification of ASB7 as ER stress responsive gene through a genome wide in silico screening for genes with ERSE." dans: PLoS ONE, Vol. 13, Issue 4, pp. e0194310, (2018) (PubMed).

Khalyfa, Qiao, Gileles-Hillel, Khalyfa, Akbarpour, Popko, Gozal: "Activation of the Integrated Stress Response and Metabolic Dysfunction in a Murine Model of Sleep Apnea." dans: American journal of respiratory cell and molecular biology, Vol. 57, Issue 4, pp. 477-486, (2017) (PubMed).

Jiang, Yun, Shi, Niu, Gao, Xie, Yu: "Downregulation of miR-384-5p attenuates rotenone-induced neurotoxicity in dopaminergic SH-SY5Y cells through inhibiting endoplasmic reticulum stress." dans: American journal of physiology. Cell physiology, Vol. 310, Issue 9, pp. C755-63, (2016) (PubMed).

Hayashi, Ouchi, Endou, Anzai: "HOXB9 acts as a negative regulator of activated human T cells in response to amino acid deficiency." dans: Immunology and cell biology, Vol. 94, Issue 6, pp. 612-7, (2016) (PubMed).

Ye, Zhang, Ancrum, Manevich, Townsend, Tew: "Glutathione S-Transferase P-Mediated Protein S-Glutathionylation of Resident Endoplasmic Reticulum Proteins Influences Sensitivity to Drug-Induced Unfolded Protein Response." dans: Antioxidants & redox signaling, (2016) (PubMed).

Synonymes et noms alternatifs relatifs à ATF4

activating transcription factor 4 (ATF4), activating transcription factor 4 (atf4), activating transcription factor 4 (Atf4), activating transcription factor 4 L homeolog (atf4.L), activating transcription factor 4a (atf4a), activating transcription factor 4b (atf4b), activating transcription factor 4 S homeolog (atf4.S), atf-4, Atf-4, ATF4, atf4, atf4-a, atf4-b, ATF4-I, atf4-ii, C/ATF, CREB-2, creb-2, CREB2, creb2, sb:eu681, TAXREB67, taxreb67, TXREB, txreb, wu:fb08f07, wu:fj01c08, wu:fk30b04, zgc:85951, zgc:171702

Protein level used designations for ATF4

  • DNA-binding protein TAXREB67
  • cAMP response element-binding protein 2
  • cAMP-dependent transcription factor ATF-4
  • cAMP-responsive element-binding protein 2
  • cyclic AMP-dependent transcription factor ATF-4
  • cyclic AMP-responsive element-binding protein 2
  • tax-responsive enhancer element B67
  • tax-responsive enhancer element-binding protein 67
  • activating transcription factor 4 (tax-responsive enhancer element B67)
  • activating transcription factor ATF-4
  • rATF-4
  • activating transcription factor 4
  • c/EBP-related ATF
  • tax-responsive enhancer element-binding protein 67 homolog
  • taxREB67 homolog
  • Activating Transcription Factor 4 -I
  • Activating Transcription Factor 4 -II
  • activating transcription factor 4 S homeolog
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